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    ABCG2 ABC-2 type transporter family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818312, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCG2
    Official Full Name
    ABC-2 type transporter family protein
    Primary source
    TAIR:AT2G37360
    Locus tag
    AT2G37360
    See related
    Araport:AT2G37360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATP-binding cassette G2; F3G5.15; F3G5_15
    Summary
    Belongs to a clade of five Arabidopsis thaliana ABCG half-transporters that are required for synthesis of an effective suberin barrier in roots and seed coats (ABCG2, ABCG6, and ABCG20) and for synthesis of an intact pollen wall (ABCG1 and ABCG16).
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    Genomic context

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    See ABCG2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (15673410..15675920, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene aluminum sensitive 3 Neighboring gene arginine/serine-rich zinc knuckle-containing protein 33 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene centrosomal protein of 135 kDa-like protein Neighboring gene membrane-associated kinase regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ABCG transporters are required for suberin and pollen wall extracellular barriers in Arabidopsis. Yadav V, et al. Plant Cell, 2014 Sep. PMID 25217507, Free PMC Article
    2. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    3. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129291.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within suberin biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ABC-2 type transporter family protein
    NP_181272.1
    • ABC-2 type transporter family protein; FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport; LOCATED IN: membrane; EXPRESSED IN: petal, hypocotyl, root, flower; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), Pigment precursor permease (InterPro:IPR005284), ABC-2 type transporter (InterPro:IPR013525), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ABC-2 type transporter family protein (TAIR:AT3G53510.1); Has 392085 Blast hits to 356271 proteins in 4132 species: Archae - 6993; Bacteria - 312114; Metazoa - 8789; Fungi - 6117; Plants - 5602; Viruses - 12; Other Eukaryotes - 52458 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15673410..15675920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129291.4 → NP_181272.1  ABC-2 type transporter family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181272.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GYL8, Q9ZUT0
      UniProtKB/TrEMBL
      A0A178VW33, A0A5S9X4X1
      Conserved Domains (1) summary
      TIGR00955
      Location:95 → 754
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZUT0.1

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