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    LIP2 lipoyltransferase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839462, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LIP2
    Official Full Name
    lipoyltransferase 2
    Primary source
    TAIR:AT1G04640
    Locus tag
    AT1G04640
    See related
    Araport:AT1G04640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    lipoyltransferase 2
    Summary
    Lipoyltransferase, located in mitochondria but not found in chloroplasts
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    Genomic context

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    See LIP2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (1292023..1293398)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene coenzyme F420 hydrogenase family / dehydrogenase, beta subunit family Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene GRIM-19 protein Neighboring gene ribonuclease P family protein / Rpp14 family protein Neighboring gene Plant self-incompatibility protein S1 family Neighboring gene holliday junction resolvase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lipoic acid metabolism in Arabidopsis thaliana: cloning and characterization of a cDNA encoding lipoyltransferase. Wada M, et al. Plant Cell Physiol, 2001 Jun. PMID 11427685
    2. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001035884.2
    NM_100343.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables lipoyl(octanoyl) transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lipoyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipoate metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein lipoylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular region HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipoyltransferase 2
    NP_001030961.1
    • lipoyltransferase 2 (LIP2); CONTAINS InterPro DOMAIN/s: Octanoyltransferase (InterPro:IPR000544), Octanoyltransferase, conserved site (InterPro:IPR020605), Biotin/lipoate A/B protein ligase (InterPro:IPR004143); BEST Arabidopsis thaliana protein match is: Biotin/lipoate A/B protein ligase family (TAIR:AT4G31050.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_171958.1
    • lipoyltransferase 2 (LIP2); CONTAINS InterPro DOMAIN/s: Octanoyltransferase (InterPro:IPR000544), Octanoyltransferase, conserved site (InterPro:IPR020605), Biotin/lipoate A/B protein ligase (InterPro:IPR004143); BEST Arabidopsis thaliana protein match is: Biotin/lipoate A/B protein ligase family (TAIR:AT4G31050.1); Has 5700 Blast hits to 5697 proteins in 1675 species: Archae - 17; Bacteria - 3180; Metazoa - 102; Fungi - 137; Plants - 98; Viruses - 0; Other Eukaryotes - 2166 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1292023..1293398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100343.3 → NP_171958.1  lipoyltransferase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171958.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23021, Q9SXP7
      UniProtKB/TrEMBL
      A0A178WI01, A0A5S9SKC3
      Conserved Domains (1) summary
      cd16444
      Location:8 → 214
      LipB; lipoyl/octanoyl transferase

    2. NM_001035884.2 → NP_001030961.1  lipoyltransferase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030961.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23021, Q9SXP7
      UniProtKB/TrEMBL
      A0A178WI01, A0A5S9SKC3
      Conserved Domains (1) summary
      cd16444
      Location:8 → 214
      LipB; lipoyl/octanoyl transferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SXP7.1

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