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    GSTU18 glutathione S-transferase TAU 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837575, updated on 18-Sep-2024

    Summary

    Official Symbol
    GSTU18
    Official Full Name
    glutathione S-transferase TAU 18
    Primary source
    TAIR:AT1G10360
    Locus tag
    AT1G10360
    See related
    Araport:AT1G10360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGSTU18; F14N23.24; F14N23_24; GLUTATHIONE S-TRANSFERASE 29; glutathione S-transferase TAU 18; GST29
    Summary
    Encodes glutathione transferase belonging to the tau class of GSTs. Naming convention according to Wagner et al. (2002).
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    Genomic context

    See GSTU18 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (3395551..3396953, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ankyrin repeat family protein Neighboring gene DNAJ heat shock family protein Neighboring gene Glutathione S-transferase family protein Neighboring gene Putative membrane lipoprotein Neighboring gene Vps51/Vps67 family (components of vesicular transport) protein

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_100910.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within toxin catabolic process TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    glutathione S-transferase TAU 18
    NP_172507.1
    • glutathione S-transferase TAU 18 (GSTU18); CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutathione S-transferase, C-terminal (InterPro:IPR004046), Glutathione S-transferase, C-terminal-like (InterPro:IPR010987), Glutathione S-transferase/chloride channel, C-terminal (InterPro:IPR017933), Glutathione S-transferase, N-terminal (InterPro:IPR004045), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: Glutathione S-transferase family protein (TAIR:AT1G10370.1); Has 5056 Blast hits to 5041 proteins in 1030 species: Archae - 0; Bacteria - 2429; Metazoa - 208; Fungi - 116; Plants - 1907; Viruses - 0; Other Eukaryotes - 396 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3395551..3396953 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100910.5NP_172507.1  glutathione S-transferase TAU 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172507.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FUS9, Q9SY78
      UniProtKB/TrEMBL
      A0A178WI86, A0A5S9TPH6
      Conserved Domains (2) summary
      cd03185
      Location:91221
      GST_C_Tau; C-terminal, alpha helical domain of Class Tau Glutathione S-transferases
      cd03058
      Location:679
      GST_N_Tau; GST_N family, Class Tau subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...