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    TIM44-2 translocase inner membrane subunit 44-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818180, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIM44-2
    Official Full Name
    translocase inner membrane subunit 44-2
    Primary source
    TAIR:AT2G36070
    Locus tag
    AT2G36070
    See related
    Araport:AT2G36070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTIM44-2; F11F19.2; F11F19_2; translocase inner membrane subunit 44-2
    Summary
    One of two genes in Arabidopsis that encode a putative subunit of the mitochondrial inner membrane translocase complex. TIM44 subunit is thought to provide the energy for translocation via hydrolysis of ATP.
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    Genomic context

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    See TIM44-2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    14
    Sequence:
    Chromosome: 2; NC_003071.7 (15144795..15148223, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ovate family protein 15 Neighboring gene MMS ZWEI homologue 3 Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene F-box family protein Neighboring gene Uncharacterized protein family (UPF0497)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification, expression, and import of components 17 and 23 of the inner mitochondrial membrane translocase from Arabidopsis. Murcha MW, et al. Plant Physiol, 2003 Apr. PMID 12692332, Free PMC Article
    2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    3. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_129166.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type protein transporter activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein targeting to mitochondrion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TIM23 mitochondrial import inner membrane translocase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    translocase inner membrane subunit 44-2
    NP_181151.3
    • translocase inner membrane subunit 44-2 (TIM44-2); FUNCTIONS IN: protein-transmembrane transporting ATPase activity; INVOLVED IN: protein targeting to mitochondrion; LOCATED IN: mitochondrion, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial inner membrane translocase complex, subunit Tim44-related (InterPro:IPR007379); BEST Arabidopsis thaliana protein match is: translocase inner membrane subunit 44-1 (TAIR:AT2G20510.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15144795..15148223 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129166.5 → NP_181151.3  translocase inner membrane subunit 44-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181151.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XF06, Q8S8E5
      UniProtKB/TrEMBL
      A0A178VXX7, A0A7G2EHS2
      Conserved Domains (2) summary
      TIGR00984
      Location:55 → 459
      3a0801s03tim44; mitochondrial import inner membrane, translocase subunit
      pfam04280
      Location:311 → 460
      Tim44; Tim44-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XF06.1

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