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    ICDH isocitrate dehydrogenase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841875, updated on 18-Sep-2024

    Summary

    Official Symbol
    ICDH
    Official Full Name
    isocitrate dehydrogenase
    Primary source
    TAIR:AT1G54340
    Locus tag
    AT1G54340
    See related
    Araport:AT1G54340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20D21.16; F20D21_16; isocitrate dehydrogenase
    Summary
    NADP-specific isocitrate dehydrogenase (ICDH)
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    Genomic context

    See ICDH in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (20283326..20286786)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene LEM3 (ligand-effect modulator 3) family protein / CDC50 family protein Neighboring gene ncRNA Neighboring gene NAC domain containing protein 20 Neighboring gene ABC transporter family protein Neighboring gene ncRNA Neighboring gene TBP-ASSOCIATED FACTOR 6B Neighboring gene sodium hydrogen exchanger 5

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    NM_001333641.1
    NM_104312.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD binding  
    enables isocitrate dehydrogenase (NADP+) activity  
    enables magnesium ion binding  

    General protein information

    Preferred Names
    isocitrate dehydrogenase
    NP_175836.1
    • isocitrate dehydrogenase (ICDH); FUNCTIONS IN: NAD or NADH binding, isocitrate dehydrogenase (NADP+) activity, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; INVOLVED IN: oxidation reduction, isocitrate metabolic process, metabolic process; LOCATED IN: peroxisome, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate dehydrogenase NADP-dependent, eukaryotic (InterPro:IPR004790), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: cytosolic NADP+-dependent isocitrate dehydrogenase (TAIR:AT1G65930.1); Has 5270 Blast hits to 5245 proteins in 1162 species: Archae - 45; Bacteria - 1280; Metazoa - 777; Fungi - 225; Plants - 439; Viruses - 0; Other Eukaryotes - 2504 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20283326..20286786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104312.3 → NP_175836.1  isocitrate dehydrogenase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175836.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLK0
      UniProtKB/TrEMBL
      A0A5S9WPN6, A0A654EU45
      Conserved Domains (1) summary
      PLN00103
      Location:1 → 409
      PLN00103; isocitrate dehydrogenase (NADP+); Provisional
    2. NM_001333641.1 → NP_001321996.1  isocitrate dehydrogenase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WDA3, A0A1P8ASL1
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