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    EMB1968 ATPase family associated with various cellular activities (AAA) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838771, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB1968
    Official Full Name
    ATPase family associated with various cellular activities (AAA)
    Primary source
    TAIR:AT1G21690
    Locus tag
    AT1G21690
    See related
    Araport:AT1G21690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    embryo defective 1968; F8K7.11; F8K7_11; replication factor C 4; RFC4
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    Genomic context

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    See EMB1968 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (7615505..7618628)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DPP6 amino-terminal domain protein Neighboring gene DPP6 N-terminal domain-like protein Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene SWITCH/sucrose nonfermenting 3C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis replication factor C4 is critical for DNA replication during the mitotic cell cycle. Qian J, et al. Plant J, 2018 Apr. PMID 29406597
    2. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Pendle AF, et al. Mol Biol Cell, 2005 Jan. PMID 15496452, Free PMC Article
    3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. critical for DNA replication during the mitotic cell cycle
      Title: Arabidopsis replication factor C4 is critical for DNA replication during the mitotic cell cycle.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001198131.1
    NM_001198132.1
    NM_102018.4
    NM_179364.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ATPase family associated with various cellular activities (AAA)
    NP_001185060.1
    • embryo defective 1968 (EMB1968); FUNCTIONS IN: in 6 functions; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: DNA replication factor C complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), Replication factor C (InterPro:IPR013748); BEST Arabidopsis thaliana protein match is: replication factor C 2 (TAIR:AT1G63160.1).
    NP_001185061.1
    • embryo defective 1968 (EMB1968); FUNCTIONS IN: in 6 functions; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: DNA replication factor C complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), Replication factor C (InterPro:IPR013748); BEST Arabidopsis thaliana protein match is: replication factor C subunit 3 (TAIR:AT1G77470.1).
    NP_564148.1
    • embryo defective 1968 (EMB1968); FUNCTIONS IN: in 6 functions; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: DNA replication factor C complex, nucleolus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), Replication factor C (InterPro:IPR013748), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921); BEST Arabidopsis thaliana protein match is: replication factor C 2 (TAIR:AT1G63160.1); Has 18128 Blast hits to 18077 proteins in 2897 species: Archae - 631; Bacteria - 10254; Metazoa - 847; Fungi - 935; Plants - 386; Viruses - 88; Other Eukaryotes - 4987 (source: NCBI BLink).
    NP_849695.1
    • embryo defective 1968 (EMB1968); FUNCTIONS IN: in 6 functions; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: DNA replication factor C complex, nucleolus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), Replication factor C (InterPro:IPR013748), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921); BEST Arabidopsis thaliana protein match is: replication factor C 2 (TAIR:AT1G63160.1); Has 15923 Blast hits to 15883 proteins in 2832 species: Archae - 621; Bacteria - 8688; Metazoa - 715; Fungi - 897; Plants - 379; Viruses - 88; Other Eukaryotes - 4535 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7615505..7618628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102018.4 → NP_564148.1  ATPase family associated with various cellular activities (AAA) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564148.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZX1, Q9XI09
      UniProtKB/TrEMBL
      A0A178WH05, A0A5S9VF89
      Conserved Domains (1) summary
      PRK00440
      Location:10 → 321
      rfc; replication factor C small subunit; Reviewed

    2. NM_001198132.1 → NP_001185061.1  ATPase family associated with various cellular activities (AAA) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185061.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HY43
      Conserved Domains (4) summary
      cd00009
      Location:26 → 166
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      PRK12402
      Location:11 → 308
      PRK12402; replication factor C small subunit 2; Reviewed
      pfam08542
      Location:256 → 309
      Rep_fac_C; Replication factor C C-terminal domain
      pfam16193
      Location:189 → 220
      AAA_assoc_2; AAA C-terminal domain

    3. NM_179364.1 → NP_849695.1  ATPase family associated with various cellular activities (AAA) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849695.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HY46
      Conserved Domains (4) summary
      cd00009
      Location:31 → 154
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      PRK00440
      Location:10 → 309
      rfc; replication factor C small subunit; Reviewed
      pfam08542
      Location:244 → 314
      Rep_fac_C; Replication factor C C-terminal domain
      pfam16193
      Location:177 → 208
      AAA_assoc_2; AAA C-terminal domain

    4. NM_001198131.1 → NP_001185060.1  ATPase family associated with various cellular activities (AAA) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185060.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HY45
      Conserved Domains (4) summary
      cd00009
      Location:26 → 159
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      PRK00440
      Location:10 → 314
      rfc; replication factor C small subunit; Reviewed
      pfam08542
      Location:249 → 319
      Rep_fac_C; Replication factor C C-terminal domain
      pfam16193
      Location:182 → 213
      AAA_assoc_2; AAA C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93ZX1.1

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