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    ATUBC2-1 Ubiquitin-conjugating enzyme family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841072, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATUBC2-1
    Official Full Name
    Ubiquitin-conjugating enzyme family protein
    Primary source
    TAIR:AT1G45050
    Locus tag
    AT1G45050
    See related
    Araport:AT1G45050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana ubiquitin-conjugating enzyme 15; F27F5.13; F27F5_13; UBC15
    Summary
    member of ubiquitin-conjugating E2-proteins
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    Genomic context

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    See ATUBC2-1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (17031211..17033269)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene copper ion binding / electron carrier protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional expression and molecular characterization of AtUBC2-1, a novel ubiquitin-conjugating enzyme (E2) from Arabidopsis thaliana. Bartling D, et al. Plant Mol Biol, 1993 Oct. PMID 8219072
    2. The CUL3A-LFH1-UBC15 ubiquitin ligase complex mediates SHORT VEGETATIVE PHASE degradation to accelerate flowering at high ambient temperature. Jin S, et al. Plant Commun, 2024 Apr 8. PMID 38213026, Free PMC Article
    3. The E2 ubiquitin-conjugating enzymes, AtUBC1 and AtUBC2, play redundant roles and are involved in activation of FLC expression and repression of flowering in Arabidopsis thaliana. Xu L, et al. Plant J, 2009 Jan. PMID 18798874
    4. The Arabidopsis Iron-Sulfur Protein GRXS17 is a Target of the Ubiquitin E3 Ligases RGLG3 and RGLG4. Nagels Durand A, et al. Plant Cell Physiol, 2016 Sep. PMID 27497447
    5. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Kraft E, et al. Plant Physiol, 2005 Dec. PMID 16339806, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The CUL3A-LFH1-UBC15 ubiquitin ligase complex mediates SHORT VEGETATIVE PHASE degradation to accelerate flowering at high ambient temperature.
      Title: The CUL3A-LFH1-UBC15 ubiquitin ligase complex mediates SHORT VEGETATIVE PHASE degradation to accelerate flowering at high ambient temperature.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001333242.1
    NM_103582.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within leaf morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of flower development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin-conjugating enzyme family protein
    NP_564493.1
    • ATUBC2-1; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin-conjugating enzyme 18 (TAIR:AT5G42990.1); Has 9046 Blast hits to 9044 proteins in 385 species: Archae - 0; Bacteria - 0; Metazoa - 3956; Fungi - 2002; Plants - 1701; Viruses - 20; Other Eukaryotes - 1367 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17031211..17033269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103582.4 → NP_564493.1  Ubiquitin-conjugating enzyme family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564493.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48952, P42743, Q67XR1, Q9MAK4
      UniProtKB/TrEMBL
      A0A178W5P1, A0A5S9WMA5
      Conserved Domains (1) summary
      pfam00179
      Location:19 → 158
      UQ_con; Ubiquitin-conjugating enzyme

    2. NM_001333242.1 → NP_001323221.1  Ubiquitin-conjugating enzyme family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AWD8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42743.2

    Gene LinkOut

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