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    AMY3 alpha-amylase-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843319, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AMY3
    Official Full Name
    alpha-amylase-like 3
    Primary source
    TAIR:AT1G69830
    Locus tag
    AT1G69830
    See related
    Araport:AT1G69830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alpha-amylase-like 3; ALPHA-AMYLASE-LIKE 3; ATAMY3; T17F3.14; T17F3_14
    Summary
    Encodes a plastid-localized alpha-amylase. Expression is reduced in the SEX4 mutant. Loss of function mutations show normal diurnal pattern of starch accumulation/degradation. Expression follows circadian rhythms.
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    Genomic context

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    See AMY3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (26288228..26293173, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene defensin-like protein Neighboring gene Defensin-like (DEFL) family protein Neighboring gene SPFH/Band 7/PHB domain-containing membrane-associated protein family Neighboring gene nitrate transporter 1:2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana AMY3 is a unique redox-regulated chloroplastic α-amylase. Seung D, et al. J Biol Chem, 2013 Nov 22. PMID 24089528, Free PMC Article
    2. The simultaneous abolition of three starch hydrolases blocks transient starch breakdown in Arabidopsis. Streb S, et al. J Biol Chem, 2012 Dec 7. PMID 23019330, Free PMC Article
    3. Regulation of Leaf Starch Degradation by Abscisic Acid Is Important for Osmotic Stress Tolerance in Plants. Thalmann M, et al. Plant Cell, 2016 Aug. PMID 27436713, Free PMC Article
    4. alpha-Amylase is not required for breakdown of transitory starch in Arabidopsis leaves. Yu TS, et al. J Biol Chem, 2005 Mar 18. PMID 15637061
    5. Starch granule biosynthesis in Arabidopsis is abolished by removal of all debranching enzymes but restored by the subsequent removal of an endoamylase. Streb S, et al. Plant Cell, 2008 Dec. PMID 19074683, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Study demonstrate that abscisic acid controls the activity of BAM1 and AMY3 in leaves under osmotic stress through the AREB/ABF-SnRK2 kinase-signaling pathway. We propose that differential regulation and isoform subfunctionalization define starch-adaptive plasticity, ensuring an optimal carbon supply for continued growth under an ever-changing environment.
      Title: Regulation of Leaf Starch Degradation by Abscisic Acid Is Important for Osmotic Stress Tolerance in Plants.
    2. Arabidopsis thaliana AMY3 is a unique redox-regulated chloroplastic alpha-amylase.
      Title: Arabidopsis thaliana AMY3 is a unique redox-regulated chloroplastic α-amylase.
    3. The additional loss of the chloroplastic alpha-amylase AMY3 partially reverts the phenotype of the quadruple DBE mutant, restoring starch granule biosynthesis.
      Title: Starch granule biosynthesis in Arabidopsis is abolished by removal of all debranching enzymes but restored by the subsequent removal of an endoamylase.
    4. alpha-amylase is not necessary for transitory starch breakdown in Arabidopsis leaves [AtAMY3]
      Title: alpha-Amylase is not required for breakdown of transitory starch in Arabidopsis leaves.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105651.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alpha-amylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables alpha-amylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within starch catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    alpha-amylase-like 3
    NP_564977.1
    • alpha-amylase-like 3 (AMY3); FUNCTIONS IN: alpha-amylase activity; INVOLVED IN: circadian rhythm, starch catabolic process; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781), Glycosyl hydrolase, family 13, catalytic domain (InterPro:IPR006047), Alpha-amylase, C-terminal beta-sheet (InterPro:IPR012850); BEST Arabidopsis thaliana protein match is: alpha-amylase-like 2 (TAIR:AT1G76130.1); Has 11240 Blast hits to 11194 proteins in 2094 species: Archae - 95; Bacteria - 8555; Metazoa - 677; Fungi - 729; Plants - 646; Viruses - 0; Other Eukaryotes - 538 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26288228..26293173 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105651.5 → NP_564977.1  alpha-amylase-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564977.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94A41, Q9CAR6
      UniProtKB/TrEMBL
      A0A178WGF4, A0A5S9WTP4, A0A654EP66
      Conserved Domains (1) summary
      PLN02784
      Location:1 → 887
      PLN02784; alpha-amylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94A41.1

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