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    GSTU12 glutathione S-transferase TAU 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843328, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GSTU12
    Official Full Name
    glutathione S-transferase TAU 12
    Primary source
    TAIR:AT1G69920
    Locus tag
    AT1G69920
    See related
    Araport:AT1G69920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GLUTATHIONE S-TRANSFERASE TAU 12; ATGSTU12; glutathione S-transferase TAU 12; T17F3.5; T17F3_5
    Summary
    Encodes glutathione transferase belonging to the tau class of GSTs. Naming convention according to Wagner et al. (2002).
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    Genomic context

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    See GSTU12 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (26334250..26335630, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Actin cross-linking protein Neighboring gene Protein kinase superfamily protein Neighboring gene glutathione S-transferase TAU 11 Neighboring gene short hypocotyl in white light1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily. Dixon DP, et al. J Exp Bot, 2009. PMID 19174456, Free PMC Article
    2. Probing the diversity of the Arabidopsis glutathione S-transferase gene family. Wagner U, et al. Plant Mol Biol, 2002 Jul. PMID 12090627
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_105660.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutathione transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glutathione metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within toxin catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione S-transferase TAU 12
    NP_177150.2
    • glutathione S-transferase TAU 12 (GSTU12); CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutathione S-transferase, C-terminal-like (InterPro:IPR010987), Glutathione S-transferase/chloride channel, C-terminal (InterPro:IPR017933), Thioredoxin-like fold (InterPro:IPR012336), Glutathione S-transferase, N-terminal (InterPro:IPR004045); BEST Arabidopsis thaliana protein match is: glutathione S-transferase tau 13 (TAIR:AT1G27130.1); Has 3943 Blast hits to 3928 proteins in 654 species: Archae - 0; Bacteria - 1408; Metazoa - 251; Fungi - 102; Plants - 1945; Viruses - 0; Other Eukaryotes - 237 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26334250..26335630 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105660.6 → NP_177150.2  glutathione S-transferase TAU 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177150.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I3V4, Q6NMS0, Q9CAS5
      UniProtKB/TrEMBL
      A0A178W5S6
      Conserved Domains (3) summary
      cd03185
      Location:121 → 250
      GST_C_Tau; C-terminal, alpha helical domain of Class Tau Glutathione S-transferases
      COG0625
      Location:36 → 243
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03058
      Location:35 → 110
      GST_N_Tau; GST_N family, Class Tau subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NMS0.2

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