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    WIN1 HOPW1-1-interacting 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844399, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WIN1
    Official Full Name
    HOPW1-1-interacting 1
    Primary source
    TAIR:AT1G80600
    Locus tag
    AT1G80600
    See related
    Araport:AT1G80600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HOPW1-1-interacting 1; T21F11.7; T21F11_7; TUMOR PRONE 5; TUP5
    Summary
    Encodes HopW1-1-Interacting protein 1 (WIN1). Interacts with the P. syringae effector HopW1-1. WIN1 is a putative acetylornithine transaminase. Modulates plant defenses against bacteria. Three WIN proteins are identified so far (WIN1: AT1G80600; WIN2: AT4G31750; WIN3: AT5G13320). Mediates red-light inhibition of seed germination.
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    Genomic context

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    See WIN1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (30298462..30300658, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene WRKY DNA-binding protein 66 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene S15/NS1, RNA-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis TUMOR PRONE5 gene encodes an acetylornithine aminotransferase required for arginine biosynthesis and root meristem maintenance in blue light. Frémont N, et al. Plant Physiol, 2013 Mar. PMID 23321422, Free PMC Article
    2. Overexpression of AtSHN1/WIN1 provokes unique defense responses. Sela D, et al. PLoS One, 2013. PMID 23922943, Free PMC Article
    3. Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1. Lee MW, et al. Plant J, 2008 May. PMID 18266921
    4. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    5. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of AtSHN1/WIN1 provokes unique defense responses.
      Title: Overexpression of AtSHN1/WIN1 provokes unique defense responses.
    2. TUMOR PRONE5 (TUP5) gene of Arabidopsis codes for acetylornithine aminotransferase that catalyzes the fourth step of arginine biosynthesis and is required for root meristem maintenance in blue light. [TUP5]
      Title: The Arabidopsis TUMOR PRONE5 gene encodes an acetylornithine aminotransferase required for arginine biosynthesis and root meristem maintenance in blue light.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_106708.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables copper ion binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-arginine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-arginine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within primary root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    HOPW1-1-interacting 1
    NP_178175.1
    • HOPW1-1-interacting 1 (WIN1); FUNCTIONS IN: N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity, copper ion binding; INVOLVED IN: defense response to bacterium; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Acetylornithine/succinylornithine aminotransferase (InterPro:IPR004636), Aminotransferase class-III (InterPro:IPR005814), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: ornithine-delta-aminotransferase (TAIR:AT5G46180.1); Has 36928 Blast hits to 36904 proteins in 2775 species: Archae - 735; Bacteria - 23598; Metazoa - 655; Fungi - 914; Plants - 410; Viruses - 17; Other Eukaryotes - 10599 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30298462..30300658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106708.4 → NP_178175.1  HOPW1-1-interacting 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178175.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56ZU0, Q8LDM4, Q9M8M7
      UniProtKB/TrEMBL
      A0A178WEJ5, A0A5S9WW69
      Conserved Domains (2) summary
      PLN00144
      Location:80 → 457
      PLN00144; acetylornithine transaminase
      TIGR00707
      Location:68 → 451
      argD; transaminase, acetylornithine/succinylornithine family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M8M7.1

    Gene LinkOut

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