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    RAD52-1 cobalt ion binding protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843472, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAD52-1
    Official Full Name
    cobalt ion binding protein
    Primary source
    TAIR:AT1G71310
    Locus tag
    AT1G71310
    See related
    Araport:AT1G71310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3I17.4; F3I17_4; ODB1; Organellar DNA-Binding protein 1; RAD52-1A; RAD52-1B.1; RAD52-1B.2; radiation sensitive 51-1
    Summary
    A protein coding gene with unknown function. The 5#Aeo UTR and the first two exons and introns of this gene overlap with a RNA coding gene TER1. TER1 (GenBank accession no. HQ401284) encodes a putative template sequence (5'-CTAAACCCTA-3') corresponding to 1.5 copies of the Arabidopsis telomere repeat (PNAS 2011, 108:73-78).
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    Genomic context

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    See RAD52-1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (26877745..26880064, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene ncRNA Neighboring gene Vps52 / Sac2 family Neighboring gene ncRNA Neighboring gene F-box family protein Neighboring gene non-intrinsic ABC protein 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RAD52-like protein ODB1 is required for the efficient excision of two mitochondrial introns spliced via first-step hydrolysis. Gualberto JM, et al. Nucleic Acids Res, 2015 Jul 27. PMID 26048959, Free PMC Article
    2. A RAD52-like single-stranded DNA binding protein affects mitochondrial DNA repair by recombination. Janicka S, et al. Plant J, 2012 Nov. PMID 22762281
    3. The effects of AtRad52 over-expression on homologous recombination in Arabidopsis. Samach A, et al. Plant J, 2018 Jul. PMID 29667244
    4. Identification of plant RAD52 homologs and characterization of the Arabidopsis thaliana RAD52-like genes. Samach A, et al. Plant Cell, 2011 Dec. PMID 22202891, Free PMC Article
    5. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. effects of over-expression on homologous recombination
      Title: The effects of AtRad52 over-expression on homologous recombination in Arabidopsis.
    2. The results demonstrate a role for the protein ODB1 in group-II intron splicing in mitochondria of Arabidopsis.
      Title: The RAD52-like protein ODB1 is required for the efficient excision of two mitochondrial introns spliced via first-step hydrolysis.
    3. Arabidopsis odb1 mutants were morphologically indistinguishable from the wild-type, but following DNA damage by genotoxic stress, they showed reduced mitochondrial homologous recombination activity.
      Title: A RAD52-like single-stranded DNA binding protein affects mitochondrial DNA repair by recombination.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105800.2
    NM_179545.3
    NM_202394.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cobalt ion binding HDA PubMed 
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in Group II intron splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within double-strand break repair via homologous recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cobalt ion binding protein
    NP_177287.1
    • cobalt ion binding; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G47870.1); Has 94 Blast hits to 94 proteins in 17 species: Archae - 0; Bacteria - 10; Metazoa - 0; Fungi - 0; Plants - 72; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).
    NP_849876.1
    • cobalt ion binding; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G47870.1); Has 94 Blast hits to 94 proteins in 17 species: Archae - 0; Bacteria - 10; Metazoa - 0; Fungi - 0; Plants - 72; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).
    NP_974123.1
    • cobalt ion binding; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G47870.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26877745..26880064 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105800.2 → NP_177287.1  cobalt ion binding protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177287.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FVV7
      UniProtKB/TrEMBL
      A0A178W7H6, A0A5S9WTJ4

    2. NM_179545.3 → NP_849876.1  cobalt ion binding protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849876.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FVV7
      UniProtKB/TrEMBL
      A0A178W7H6, A0A5S9WTJ4

    3. NM_202394.2 → NP_974123.1  cobalt ion binding protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974123.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7V2, F4I8H5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FVV7.1

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