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    BCE2 2-oxoacid dehydrogenases acyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819869, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BCE2
    Official Full Name
    2-oxoacid dehydrogenases acyltransferase family protein
    Primary source
    TAIR:AT3G06850
    Locus tag
    AT3G06850
    See related
    Araport:AT3G06850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DARK INDUCIBLE 3; DIN3; LTA1
    Summary
    dihydrolipoamide branched chain acyltransferase
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    Genomic context

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    See BCE2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (2157908..2160669, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase-like protein Neighboring gene Mov34/MPN/PAD-1 family protein Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily Neighboring gene uncharacterized protein Neighboring gene multifunctional protein 2 Neighboring gene vitellogenin-like protein Neighboring gene proline-rich family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dihydrolipoyl acyltransferase (BCE2) subunit of the plant branched-chain alpha-ketoacid dehydrogenase complex forms a 24-mer core with octagonal symmetry. Mooney BP, et al. Protein Sci, 2000 Jul. PMID 10933498, Free PMC Article
    2. Leucine and its keto acid enhance the coordinated expression of genes for branched-chain amino acid catabolism in Arabidopsis under sugar starvation. Fujiki Y, et al. FEBS Lett, 2001 Jun 15. PMID 11418132
    3. Isolation and characterization of cDNA clones for the e1beta and E2 subunits of the branched-chain alpha-ketoacid dehydrogenase complex in Arabidopsis. Fujiki Y, et al. J Biol Chem, 2000 Feb 25. PMID 10681595
    4. Multiple signaling pathways in gene expression during sugar starvation. Pharmacological analysis of din gene expression in suspension-cultured cells of Arabidopsis. Fujiki Y, et al. Plant Physiol, 2000 Nov. PMID 11080291, Free PMC Article
    5. Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Taylor NL, et al. Plant Physiol, 2004 Feb. PMID 14764908, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111565.6
    NM_180196.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding HDA PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to sucrose starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to absence of light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to sucrose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2-oxoacid dehydrogenases acyltransferase family protein
    NP_187341.1
    • BCE2; FUNCTIONS IN: acetyltransferase activity, dihydrolipoamide branched chain acyltransferase activity, alpha-ketoacid dehydrogenase activity, zinc ion binding; INVOLVED IN: response to light stimulus, response to sucrose stimulus; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 2-oxo acid dehydrogenase, lipoyl-binding site (InterPro:IPR003016), E3 binding (InterPro:IPR004167), 2-oxoacid dehydrogenase acyltransferase, catalytic domain (InterPro:IPR001078), Single hybrid motif (InterPro:IPR011053), Biotin/lipoyl attachment (InterPro:IPR000089), Lipoamide Acyltransferase (InterPro:IPR015761); BEST Arabidopsis thaliana protein match is: Dihydrolipoamide acetyltransferase, long form protein (TAIR:AT1G54220.2); Has 20964 Blast hits to 19078 proteins in 2320 species: Archae - 110; Bacteria - 11780; Metazoa - 568; Fungi - 442; Plants - 349; Viruses - 0; Other Eukaryotes - 7715 (source: NCBI BLink).
    NP_850527.1
    • BCE2; FUNCTIONS IN: acetyltransferase activity, dihydrolipoamide branched chain acyltransferase activity, alpha-ketoacid dehydrogenase activity, zinc ion binding; INVOLVED IN: response to light stimulus, response to sucrose stimulus; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 2-oxo acid dehydrogenase, lipoyl-binding site (InterPro:IPR003016), E3 binding (InterPro:IPR004167), 2-oxoacid dehydrogenase acyltransferase, catalytic domain (InterPro:IPR001078), Single hybrid motif (InterPro:IPR011053), Biotin/lipoyl attachment (InterPro:IPR000089), Lipoamide Acyltransferase (InterPro:IPR015761); BEST Arabidopsis thaliana protein match is: Dihydrolipoamide acetyltransferase, long form protein (TAIR:AT1G54220.2); Has 20964 Blast hits to 19078 proteins in 2320 species: Archae - 110; Bacteria - 11780; Metazoa - 568; Fungi - 442; Plants - 349; Viruses - 0; Other Eukaryotes - 7715 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2157908..2160669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111565.6 → NP_187341.1  2-oxoacid dehydrogenases acyltransferase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187341.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64968, Q9M724, Q9M7Z1
      UniProtKB/TrEMBL
      A0A178VL69, A0A5S9X9U1, A0A654F6G8
      Conserved Domains (1) summary
      PLN02528
      Location:78 → 483
      PLN02528; 2-oxoisovalerate dehydrogenase E2 component

    2. NM_180196.3 → NP_850527.1  2-oxoacid dehydrogenases acyltransferase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850527.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64968, Q9M724, Q9M7Z1
      UniProtKB/TrEMBL
      A0A178VL69, A0A5S9X9U1, A0A654F6G8
      Conserved Domains (1) summary
      PLN02528
      Location:78 → 483
      PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M7Z1.1

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