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    PERK1 proline extensin-like receptor kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822051, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PERK1
    Official Full Name
    proline extensin-like receptor kinase 1
    Primary source
    TAIR:AT3G24550
    Locus tag
    AT3G24550
    See related
    Araport:AT3G24550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPERK1; MOB24.11; proline extensin-like receptor kinase 1; proline-rich extensin-like receptor kinase 1
    Summary
    Encodes a member of the proline-rich extensin-like receptor kinase (PERK) family. This family consists of 15 predicted receptor kinases (PMID: 15653807).
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    Genomic context

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    See PERK1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (8960095..8963568)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Beta-galactosidase related protein Neighboring gene ncRNA Neighboring gene Adenine nucleotide alpha hydrolases-like superfamily protein Neighboring gene Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The proline-rich, extensin-like receptor kinase-1 (PERK1) gene is rapidly induced by wounding. Silva NF, et al. Plant Mol Biol, 2002 Nov. PMID 12374299
    2. Members of the Plant CRK Superfamily Are Capable of Trans- and Autophosphorylation of Tyrosine Residues. Nemoto K, et al. J Biol Chem, 2015 Jul 3. PMID 25969537, Free PMC Article
    3. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822
    4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    5. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_113366.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
    acts_upstream_of_or_within response to fungus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proline extensin-like receptor kinase 1
    NP_189098.1
    • proline extensin-like receptor kinase 1 (PERK1); FUNCTIONS IN: protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation, response to fungus, response to wounding; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: roline-rich extensin-like receptor kinase 4 (TAIR:AT2G18470.1); Has 334655 Blast hits to 210931 proteins in 5790 species: Archae - 702; Bacteria - 55907; Metazoa - 123975; Fungi - 45755; Plants - 52676; Viruses - 6745; Other Eukaryotes - 48895 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8960095..8963568
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113366.3 → NP_189098.1  proline extensin-like receptor kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189098.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z3E1, Q6QJ27, Q6QJ28, Q94JZ6, Q9LV48
      UniProtKB/TrEMBL
      A0A178VAK0
      Conserved Domains (2) summary
      smart00221
      Location:286 → 553
      STYKc; Protein kinase; unclassified specificity
      cl21453
      Location:286 → 555
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LV48.1

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