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    WIP3 WPP domain interacting protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820536, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WIP3
    Official Full Name
    WPP domain interacting protein 3
    Primary source
    TAIR:AT3G13360
    Locus tag
    AT3G13360
    See related
    Araport:AT3G13360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    WPP domain interacting protein 3
    Summary
    Encodes an outer nuclear membrane protein that anchors RanGAP1 to the nuclear envelope. It interacts with SUN proteins and is required for maintaining the elongated nuclear shape of epidermal cells.
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    Genomic context

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    See WIP3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (4338250..4340446, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene HMG (high mobility group) box protein with ARID/BRIGHT DNA-binding domain-containing protein Neighboring gene formin-like protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins. Xu XM, et al. Curr Biol, 2007 Jul 3. PMID 17600715
    2. SUN anchors pollen WIP-WIT complexes at the vegetative nuclear envelope and is necessary for pollen tube targeting and fertility. Zhou X, et al. J Exp Bot, 2015 Dec. PMID 26409047, Free PMC Article
    3. Novel plant SUN-KASH bridges are involved in RanGAP anchoring and nuclear shape determination. Zhou X, et al. J Cell Biol, 2012 Jan 23. PMID 22270916, Free PMC Article
    4. Plant nuclear shape is independently determined by the SUN-WIP-WIT2-myosin XI-i complex and CRWN1. Zhou X, et al. Nucleus, 2015. PMID 25759303, Free PMC Article
    5. The TOPLESS interactome: a framework for gene repression in Arabidopsis. Causier B, et al. Plant Physiol, 2012 Jan. PMID 22065421, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001338045.1
    NM_112181.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within nucleus organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WPP domain interacting protein 3
    NP_566455.1
    • WPP domain interacting protein 3 (WIP3); BEST Arabidopsis thaliana protein match is: WPP domain interacting protein 1 (TAIR:AT4G26455.1); Has 169 Blast hits to 165 proteins in 48 species: Archae - 0; Bacteria - 16; Metazoa - 21; Fungi - 13; Plants - 65; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4338250..4340446 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112181.5 → NP_566455.1  WPP domain interacting protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566455.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94AV5, Q9LTT2
      UniProtKB/TrEMBL
      A0A178V5S4
      Conserved Domains (1) summary
      COG4717
      Location:250 → 407
      YhaN; Uncharacterized protein YhaN, contains AAA domain [Function unknown]

    2. NM_001338045.1 → NP_001327578.1  WPP domain interacting protein 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSR4, A0A654F6R3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94AV5.1

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