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    disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843291, updated on 18-Sep-2024

    Summary

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    Official Full Name
    disease resistance protein (TIR-NBS-LRR class)
    Primary source
    TAIR:AT1G69550
    Locus tag
    AT1G69550
    See related
    Araport:AT1G69550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10D13.24; F10D13_24
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (26148021..26153600, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene expansin A1 Neighboring gene AGAMOUS-like 94 Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene myb domain protein 105

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_105624.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    disease resistance protein (TIR-NBS-LRR class)
    NP_564971.2
    • disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) (TAIR:AT5G11250.1); Has 8455 Blast hits to 8197 proteins in 261 species: Archae - 0; Bacteria - 113; Metazoa - 3; Fungi - 4; Plants - 8303; Viruses - 0; Other Eukaryotes - 32 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26148021..26153600 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105624.5 → NP_564971.2  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564971.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4I270, Q9C784
      Conserved Domains (7) summary
      cd09293
      Location:1053 → 1214
      AMN1; Antagonist of mitotic exit network protein 1
      cd00116
      Location:884 → 1132
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:934 → 957
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00931
      Location:258 → 510
      NB-ARC; NB-ARC domain
      pfam01582
      Location:80 → 242
      TIR; TIR domain
      pfam07725
      Location:671 → 690
      LRR_3; Leucine Rich Repeat
      pfam13191
      Location:254 → 372
      AAA_16; AAA ATPase domain
    Nucleotide Protein
    Heading Accession and Version

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