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    ABCG39 pleiotropic drug resistance 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843013, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCG39
    Official Full Name
    pleiotropic drug resistance 11
    Primary source
    TAIR:AT1G66950
    Locus tag
    AT1G66950
    See related
    Araport:AT1G66950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATP-binding cassette G39; ATPDR11; PDR11; pleiotropic drug resistance 11; PLEIOTROPIC DRUG RESISTANCE 11; T4O24.9; T4O24_9
    Summary
    Encodes a plasma membrane-localized ABC transporter. Confers tolerance to herbicide paraquat.
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    Genomic context

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    See ABCG39 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    20
    Sequence:
    Chromosome: 1; NC_003070.9 (24978121..24984619)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein Neighboring gene kinase-like protein Neighboring gene Terpenoid cyclases family protein Neighboring gene SHV3-like 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of AtPDR11, a plasma membrane-localized ABC transporter, confers paraquat tolerance in Arabidopsis thaliana. Xi J, et al. Plant J, 2012 Mar. PMID 22026747
    2. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Loss-of-function mutations of AtPDR11 result in a paraquat resistance phenotype at the seedling stage due to reduced import of paraquat in Arabidopsis.
      Title: Loss of AtPDR11, a plasma membrane-localized ABC transporter, confers paraquat tolerance in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105366.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to reactive oxygen species IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within xenobiotic transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pleiotropic drug resistance 11
    NP_176867.2
    • pleiotropic drug resistance 11 (PDR11); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: drug transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), Plant PDR ABC transporter associated (InterPro:IPR013581), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: pleiotropic drug resistance 6 (TAIR:AT2G36380.1); Has 357151 Blast hits to 273757 proteins in 3981 species: Archae - 7090; Bacteria - 287486; Metazoa - 9208; Fungi - 6204; Plants - 5777; Viruses - 4; Other Eukaryotes - 41382 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24978121..24984619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105366.4 → NP_176867.2  pleiotropic drug resistance 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176867.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7PC84, Q9C623, Q9FZI3
      UniProtKB/TrEMBL
      A0A178WE29
      Conserved Domains (6) summary
      cd03232
      Location:850 → 1088
      ABCG_PDR_domain2; Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters
      PLN03140
      Location:14 → 1454
      PLN03140; ABC transporter G family member; Provisional
      pfam01061
      Location:1183 → 1388
      ABC2_membrane; ABC-2 type transporter
      pfam08370
      Location:744 → 810
      PDR_assoc; Plant PDR ABC transporter associated
      pfam14510
      Location:94 → 169
      ABC_trans_N; ABC-transporter extracellular N-terminal
      cl21455
      Location:180 → 430
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7PC84.1

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