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    RD20 Caleosin-related family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817901, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RD20
    Official Full Name
    Caleosin-related family protein
    Primary source
    TAIR:AT2G33380
    Locus tag
    AT2G33380
    See related
    Araport:AT2G33380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana caleosin 3; AtCLO3; AtRD20; caleosin 3; CALEOSIN 3; CLO-3; CLO3; F4P9.15; F4P9_15; peroxygenase 3; PXG3; RESPONSIVE TO DESSICATION 20
    Summary
    Encodes a calcium binding protein whose mRNA is induced upon treatment with NaCl, ABA and in response to dessication. mRNA expression under drought conditions is apparent particularly in leaves and flowers. Isoform of caleosin with a role as a peroxygenase involved in oxylipin metabolism during biotic and abiotic stress. Involved in the production of 2-hydroxy-octadecatrienoic acid. The peroxygenase has a narrow substrate specificity thus acting as a fatty acid hydroperoxide reductase in vivo.
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    Genomic context

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    See RD20 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (14144831..14146555, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cadherin EGF LAG seven-pass G-type receptor, putative (DUF3527) Neighboring gene Ribosomal protein L14p/L23e family protein Neighboring gene actin-related protein C2B Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The proper localization of RESPONSIVE TO DESICCATION 20 in lipid droplets depends on their biogenesis induced by STRESS-RELATED PROTEINS in vegetative tissues. Park KY, et al. Biochem Biophys Res Commun, 2018 Jan 8. PMID 29247649
    2. An Arabidopsis gene encoding a Ca2+-binding protein is induced by abscisic acid during dehydration. Takahashi S, et al. Plant Cell Physiol, 2000 Jul. PMID 10965948
    3. Involvement of the caleosin/peroxygenase RD20 in the control of cell death during Arabidopsis responses to pathogens. Hanano A, et al. Plant Signal Behav, 2015. PMID 25830533, Free PMC Article
    4. The reductase activity of the Arabidopsis caleosin RESPONSIVE TO DESSICATION20 mediates gibberellin-dependent flowering time, abscisic acid sensitivity, and tolerance to oxidative stress. Blée E, et al. Plant Physiol, 2014 Sep. PMID 25056921, Free PMC Article
    5. Roles of a membrane-bound caleosin and putative peroxygenase in biotic and abiotic stress responses in Arabidopsis. Partridge M, et al. Plant Physiol Biochem, 2009 Sep. PMID 19467604

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The caleosin RD20/CLO3 regulates lateral root development in response to abscisic acid and regulates flowering time in conjunction with the caleosin CLO7.
      Title: The caleosin RD20/CLO3 regulates lateral root development in response to abscisic acid and regulates flowering time in conjunction with the caleosin CLO7.
    2. The stress induced caleosin, RD20/CLO3, acts as a negative regulator of GPA1 in Arabidopsis.
      Title: The stress induced caleosin, RD20/CLO3, acts as a negative regulator of GPA1 in Arabidopsis.
    3. Our data suggest that Arabidopsis SRPs play roles as positive factors for LD biogenesis to provide a proper localization of LD-localizing proteins in vegetative tissues.
      Title: The proper localization of RESPONSIVE TO DESICCATION 20 in lipid droplets depends on their biogenesis induced by STRESS-RELATED PROTEINS in vegetative tissues.
    4. the major function of RD20 is to generate oxylipins modulating oxidative status and cell death.
      Title: Involvement of the caleosin/peroxygenase RD20 in the control of cell death during Arabidopsis responses to pathogens.
    5. overexpressing plants exhibit elevated levels of reactive oxygen species associated with early gibberellin-dependent flowering and abscisic acid hypersensitivity at seed germination
      Title: The reductase activity of the Arabidopsis caleosin RESPONSIVE TO DESSICATION20 mediates gibberellin-dependent flowering time, abscisic acid sensitivity, and tolerance to oxidative stress.
    6. Data show the expression profiles for six genes for At1g71000, At4g18430, At2g33380, At4g30460, At3g22570 and At5g66400 during salt stress response.
      Title: A spatio-temporal understanding of growth regulation during the salt stress response in Arabidopsis.
    7. RD20 has a role in drought tolerance through stomatal control under water deficit conditions.
      Title: RD20, a stress-inducible caleosin, participates in stomatal control, transpiration and drought tolerance in Arabidopsis thaliana.
    8. Clo-3 is part of an oxylipin pathway induced by multiple stresses and may also generate fatty acid derived anti-fungal compounds for plant defence. [Clo-3] [caleosin 3]
      Title: Roles of a membrane-bound caleosin and putative peroxygenase in biotic and abiotic stress responses in Arabidopsis.
    9. Data report that MSI1 can bind to the chromatin of the drought-inducible downstream target RD20 and suggest a new role for MSI1 in the negative regulation of the Arabidopsis drought-stress response.
      Title: Arabidopsis MSI1 is required for negative regulation of the response to drought stress.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036395.1
    NM_128898.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calcium ion binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables plant seed peroxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables plant seed peroxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within (R)-2-hydroxy-alpha-linolenic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within oxylipin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of reactive oxygen species metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    NOT involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to desiccation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to desiccation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to fungus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salicylic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in monolayer-surrounded lipid storage body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Caleosin-related family protein
    NP_001031472.1
    • RESPONSIVE TO DESSICATION 20 (RD20); FUNCTIONS IN: lipoxygenase activity, calcium ion binding; INVOLVED IN: in 7 processes; LOCATED IN: chloroplast membrane, microsome, vacuole; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Caleosin related (InterPro:IPR007736); BEST Arabidopsis thaliana protein match is: caleosin-related family protein (TAIR:AT5G29560.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_180896.1
    • RESPONSIVE TO DESSICATION 20 (RD20); FUNCTIONS IN: lipoxygenase activity, calcium ion binding; INVOLVED IN: in 7 processes; LOCATED IN: chloroplast membrane, microsome, vacuole; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Caleosin related (InterPro:IPR007736); BEST Arabidopsis thaliana protein match is: seed gene 1 (TAIR:AT4G26740.1); Has 344 Blast hits to 339 proteins in 61 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 60; Plants - 279; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14144831..14146555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128898.4 → NP_180896.1  Caleosin-related family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180896.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG65, O22788
      UniProtKB/TrEMBL
      A0A178VZI0, A0A5S9X3N0
      Conserved Domains (1) summary
      pfam05042
      Location:57 → 226
      Caleosin; Caleosin related protein

    2. NM_001036395.1 → NP_001031472.1  Caleosin-related family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031472.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22788
      Conserved Domains (1) summary
      pfam05042
      Location:57 → 183
      Caleosin; Caleosin related protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22788.1

    Gene LinkOut

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