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    AOP3 2-oxoglutarate-dependent dioxygenase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828104, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AOP3
    Official Full Name
    2-oxoglutarate-dependent dioxygenase
    Primary source
    TAIR:AT4G03050
    Locus tag
    AT4G03050
    See related
    Araport:AT4G03050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T4I9.7; T4I9_7
    Summary
    Transcriptional silent in leaf tissues of ecotype Col. The transcribed allele in ecotype Ler encodes a 2-oxoglutarate-dependent dioxygenase which is involved in glucosinolate biosynthesis. The natural variation in this locus explains the diversification of hydroxyalkyl glucosinolates among different ecotypes of Arabidopsis.
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    Genomic context

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    See AOP3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (1343845..1346436)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. Kliebenstein DJ, et al. Plant Cell, 2001 Mar. PMID 11251105, Free PMC Article
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001340416.1
    NM_001340417.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    NOT involved_in glucosinolate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosinolate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    2-oxoglutarate-dependent dioxygenase
    NP_001319854.1
    • AOP3; FUNCTIONS IN: oxidoreductase activity, iron ion binding; LOCATED IN: endomembrane system; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Isopenicillin N synthase (InterPro:IPR002283), Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein (TAIR:AT4G03070.1); Has 6223 Blast hits to 6097 proteins in 833 species: Archae - 0; Bacteria - 725; Metazoa - 54; Fungi - 398; Plants - 4262; Viruses - 57; Other Eukaryotes - 727 (source: NCBI BLink).
    NP_001319855.1
    • AOP3; FUNCTIONS IN: oxidoreductase activity, iron ion binding; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Isopenicillin N synthase (InterPro:IPR002283), Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein (TAIR:AT4G03070.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1343845..1346436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340416.1 → NP_001319854.1  2-oxoglutarate-dependent dioxygenase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JHY7, F4JHY8, Q9ZTA1
      UniProtKB/TrEMBL
      A0A5S9XPS2, A0A654FLF5, Q944X1
      Conserved Domains (2) summary
      PLN02365
      Location:32 → 385
      PLN02365; 2-oxoglutarate-dependent dioxygenase
      pfam03171
      Location:271 → 356
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

    2. NM_001340417.1 → NP_001319855.1  2-oxoglutarate-dependent dioxygenase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JHY7, F4JHY8, Q9ZTA1
      UniProtKB/TrEMBL
      A0A5S9XPS2, A0A654FLF5, Q944X1
      Conserved Domains (2) summary
      PLN02365
      Location:32 → 385
      PLN02365; 2-oxoglutarate-dependent dioxygenase
      pfam03171
      Location:271 → 356
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZTA1.1

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