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    FADA fatty acid desaturase A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828811, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FADA
    Official Full Name
    fatty acid desaturase A
    Primary source
    TAIR:AT4G27030
    Locus tag
    AT4G27030
    See related
    Araport:AT4G27030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10M23.370; F10M23_370; FAD4; FATTY ACID DESATURASE 4; fatty acid desaturase A
    Summary
    Encodes an unusual palmitate desaturase that is highly substrate specific. It introduces a delta-3 trans double bond at palmitate at the sn-2 position of phosphatidylglycerol.
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    Genomic context

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    See FADA in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (13571813..13573070)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene ribosome 60S biogenesis amino-terminal protein Neighboring gene inositol-1,4,5-trisphosphate 5-phosphatase Neighboring gene EAP30/Vps36 family protein Neighboring gene F-box/RNI-like superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mutant of Arabidopsis lacking a chloroplast-specific lipid. Browse J, et al. Science, 1985 Feb 15. PMID 17796728
    2. FATTY ACID DESATURASE4 of Arabidopsis encodes a protein distinct from characterized fatty acid desaturases. Gao J, et al. Plant J, 2009 Dec. PMID 19682287
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_118837.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables palmitoyl-[glycerolipid] 3-(E)-desaturase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables palmitoyl-[glycerolipid] 3-(E)-desaturase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables palmitoyl-[glycerolipid] 3-(E)-desaturase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphatidylglycerol metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unsaturated fatty acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast NAS
    Non-traceable Author Statement
    more info
    		  
    located_in chloroplast membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fatty acid desaturase A
    NP_194433.1
    • fatty acid desaturase A (FADA); FUNCTIONS IN: Delta 3-trans hexadecenoic acid phosphatidylglycerol desaturase activity; INVOLVED IN: response to karrikin, phosphatidylglycerol metabolic process, unsaturated fatty acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Kua-ubiquitin conjugating enzyme hybrid, localisation (InterPro:IPR019547); BEST Arabidopsis thaliana protein match is: Kua-ubiquitin conjugating enzyme hybrid localisation domain (TAIR:AT1G62190.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13571813..13573070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118837.2 → NP_194433.1  fatty acid desaturase A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194433.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94EW9, Q9SZ42
      UniProtKB/TrEMBL
      A0A178UUY9, A0A5S9XWX8, A0A654FT47
      Conserved Domains (1) summary
      pfam10520
      Location:137 → 305
      TMEM189_B_dmain; B domain of TMEM189, localization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SZ42.1

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