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    PAP2 phytochrome-associated protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829029, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAP2
    Official Full Name
    phytochrome-associated protein 2
    Primary source
    TAIR:AT4G29080
    Locus tag
    AT4G29080
    See related
    Araport:AT4G29080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19B15.110; F19B15_110; IAA27; indole-3-acetic acid inducible 27; phytochrome-associated protein 2
    Summary
    phytochrome-associated protein 2 (PAP2)
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    Genomic context

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    See PAP2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14323296..14325361, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Concanavalin A-like lectin protein kinase family protein Neighboring gene elongation factor Ts family protein Neighboring gene Phospholipase A2 family protein Neighboring gene Ribonuclease H-like superfamily protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mitochondrial prolyl aminopeptidase PAP2 releases N-terminal proline and regulates proline homeostasis during stress response. Ghifari AS, et al. Plant J, 2020 Dec. PMID 32920905
    2. AtPAP2 is a tail-anchored protein in the outer membrane of chloroplasts and mitochondria. Sun F, et al. Plant Signal Behav, 2012 Aug. PMID 22751362, Free PMC Article
    3. RNA editing of cytochrome c maturation transcripts is responsive to the energy status of leaf cells in Arabidopsis thaliana. Sun Y, et al. Mitochondrion, 2017 Jul. PMID 28478183
    4. Genetics of Aux/IAA and ARF action in plant growth and development. Liscum E, et al. Plant Mol Biol, 2002 Jun-Jul. PMID 12036262
    5. AUXIN RESPONSE FACTOR8 regulates Arabidopsis petal growth by interacting with the bHLH transcription factor BIGPETALp. Varaud E, et al. Plant Cell, 2011 Mar. PMID 21421811, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A mitochondrial prolyl aminopeptidase PAP2 releases N-terminal proline and regulates proline homeostasis during stress response.
      Title: A mitochondrial prolyl aminopeptidase PAP2 releases N-terminal proline and regulates proline homeostasis during stress response.
    2. The authors proposed that AtPAP2 may influence cytochrome c biogenesis by modulating RNA editing through its interaction with MORF proteins.
      Title: RNA editing of cytochrome c maturation transcripts is responsive to the energy status of leaf cells in Arabidopsis thaliana.
    3. AtPAP2 is located on, but not imported across the outer membrane (OM) of chloroplasts and mitochondria.
      Title: AtPAP2 is a tail-anchored protein in the outer membrane of chloroplasts and mitochondria.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_119052.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to auxin TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phytochrome-associated protein 2
    NP_194637.1
    • phytochrome-associated protein 2 (PAP2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to auxin stimulus, regulation of translation; LOCATED IN: intracellular, nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), AUX/IAA protein (InterPro:IPR003311); BEST Arabidopsis thaliana protein match is: indoleacetic acid-induced protein 8 (TAIR:AT2G22670.4); Has 2237 Blast hits to 2234 proteins in 81 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 2235; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14323296..14325361 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119052.4 → NP_194637.1  phytochrome-associated protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194637.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZSY8
      UniProtKB/TrEMBL
      A0A178V3Y7, A0A5S9XWX6, D3K0K2
      Conserved Domains (1) summary
      pfam02309
      Location:42 → 296
      AUX_IAA; AUX/IAA family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZSY8.1

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