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    CSY2 citrate synthase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825044, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CSY2
    Official Full Name
    citrate synthase 2
    Primary source
    TAIR:AT3G58750
    Locus tag
    AT3G58750
    See related
    Araport:AT3G58750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    citrate synthase 2
    Summary
    Encodes a peroxisomal citrate synthase that is expressed throughout seedling and shoot development.
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    Genomic context

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    See CSY2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (21724306..21728137, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene vacuolar ATP synthase subunit D (VATD) / V-ATPase D subunit / vacuolar proton pump D subunit (VATPD) Neighboring gene citrate synthase 1 Neighboring gene Integrin-linked protein kinase family Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reduced peroxisomal citrate synthase activity increases substrate availability for polyhydroxyalkanoate biosynthesis in plant peroxisomes. Tilbrook K, et al. Plant Biotechnol J, 2014 Oct. PMID 24944109
    2. Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. Pracharoenwattana I, et al. Plant Cell, 2005 Jul. PMID 15923350, Free PMC Article
    3. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Reduced peroxisomal citrate synthase activity in a peroxisomal polyhydroxyalkanoate (PHA)-producing Arabidopsis line increases PHA accumulation
      Title: Reduced peroxisomal citrate synthase activity increases substrate availability for polyhydroxyalkanoate biosynthesis in plant peroxisomes.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_115737.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables citrate (Si)-synthase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid beta-oxidation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 
    located_in secretory vesicle HDA PubMed 

    General protein information

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    Preferred Names
    citrate synthase 2
    NP_191434.1
    • citrate synthase 2 (CSY2); FUNCTIONS IN: citrate (SI)-synthase activity; INVOLVED IN: fatty acid beta-oxidation, tricarboxylic acid cycle; LOCATED IN: peroxisome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Citrate synthase, type II (InterPro:IPR010953), Citrate synthase-like, large alpha subdomain (InterPro:IPR016142), Citrate synthase active site (InterPro:IPR019810), Citrate synthase-like, core (InterPro:IPR016141), Citrate synthase-like (InterPro:IPR002020); BEST Arabidopsis thaliana protein match is: citrate synthase 3 (TAIR:AT2G42790.1); Has 13448 Blast hits to 13446 proteins in 3190 species: Archae - 173; Bacteria - 8550; Metazoa - 303; Fungi - 319; Plants - 178; Viruses - 0; Other Eukaryotes - 3925 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      21724306..21728137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115737.3 → NP_191434.1  citrate synthase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191434.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q570I4, Q9LXS6
      UniProtKB/TrEMBL
      A0A178VNV2, A0A5S9XM11, A0A654FJ02
      Conserved Domains (1) summary
      PLN02456
      Location:32 → 485
      PLN02456; citrate synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LXS6.1

    Gene LinkOut

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