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    CSY1 citrate synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825043, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CSY1
    Official Full Name
    citrate synthase 1
    Primary source
    TAIR:AT3G58740
    Locus tag
    AT3G58740
    See related
    Araport:AT3G58740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    citrate synthase 1
    Summary
    Encodes a peroxisomal citrate synthase that is expressed in siliques and developing seeds.
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    Genomic context

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    See CSY1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (21720773..21723790, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene WRKY DNA-binding protein 69 Neighboring gene RING/U-box superfamily protein Neighboring gene vacuolar ATP synthase subunit D (VATD) / V-ATPase D subunit / vacuolar proton pump D subunit (VATPD) Neighboring gene citrate synthase 2 Neighboring gene Integrin-linked protein kinase family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. Pracharoenwattana I, et al. Plant Cell, 2005 Jul. PMID 15923350, Free PMC Article
    2. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_115736.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables citrate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    citrate synthase 1
    NP_191433.1
    • citrate synthase 1 (CSY1); FUNCTIONS IN: citrate (SI)-synthase activity, transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; INVOLVED IN: cellular carbohydrate metabolic process, tricarboxylic acid cycle; LOCATED IN: peroxisome; EXPRESSED IN: fruit; EXPRESSED DURING: seed development stages; CONTAINS InterPro DOMAIN/s: Citrate synthase-like, large alpha subdomain (InterPro:IPR016142), Citrate synthase active site (InterPro:IPR019810), Citrate synthase-like (InterPro:IPR002020), Citrate synthase-like, core (InterPro:IPR016141); BEST Arabidopsis thaliana protein match is: citrate synthase 2 (TAIR:AT3G58750.1); Has 13123 Blast hits to 13123 proteins in 3164 species: Archae - 173; Bacteria - 8422; Metazoa - 267; Fungi - 318; Plants - 178; Viruses - 0; Other Eukaryotes - 3765 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      21720773..21723790 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115736.2 → NP_191433.1  citrate synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191433.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LXS7
      UniProtKB/TrEMBL
      A0A178VEL4, A0A654FJ15
      Conserved Domains (1) summary
      PLN02456
      Location:29 → 478
      PLN02456; citrate synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LXS7.1

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