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    Mitogen activated protein kinase kinase kinase-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825033, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Mitogen activated protein kinase kinase kinase-like protein
    Primary source
    TAIR:AT3G58640
    Locus tag
    AT3G58640
    See related
    Araport:AT3G58640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    18
    Sequence:
    Chromosome: 3; NC_003074.8 (21686741..21693928, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene tetratricopetide-repeat thioredoxin-like 4 Neighboring gene sequence-specific DNA binding transcription factor Neighboring gene GPI-anchored adhesin-like protein Neighboring gene Ribosomal protein L1p/L10e family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells. Wang H, et al. J Integr Plant Biol, 2023 Sep. PMID 37226855
    2. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_115726.3
    NM_180387.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Mitogen activated protein kinase kinase kinase-like protein
    NP_567072.1
    • Mitogen activated protein kinase kinase kinase-related; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT2G31010.2); Has 125470 Blast hits to 123383 proteins in 4957 species: Archae - 158; Bacteria - 13680; Metazoa - 47784; Fungi - 11367; Plants - 32991; Viruses - 518; Other Eukaryotes - 18972 (source: NCBI BLink).
    NP_850718.1
    • Mitogen activated protein kinase kinase kinase-related; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT2G31010.2); Has 125614 Blast hits to 123525 proteins in 4988 species: Archae - 158; Bacteria - 13731; Metazoa - 47851; Fungi - 11388; Plants - 32996; Viruses - 518; Other Eukaryotes - 18972 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      21686741..21693928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180387.2 → NP_850718.1  Mitogen activated protein kinase kinase kinase-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850718.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VF38, A0A384KGV8, A0A654FJ04, Q94AB2
      Conserved Domains (2) summary
      cd13999
      Location:559 → 801
      STKc_MAP3K-like; Catalytic domain of Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase-like Serine/Threonine kinases
      pfam14381
      Location:56 → 249
      EDR1; Ethylene-responsive protein kinase Le-CTR1

    2. NM_115726.3 → NP_567072.1  Mitogen activated protein kinase kinase kinase-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567072.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VF38, A0A384KGV8, A0A654FJ04, Q94AB2
      Conserved Domains (2) summary
      cd13999
      Location:559 → 801
      STKc_MAP3K-like; Catalytic domain of Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase-like Serine/Threonine kinases
      pfam14381
      Location:56 → 249
      EDR1; Ethylene-responsive protein kinase Le-CTR1
    Nucleotide Protein
    Heading Accession and Version

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