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    RAB8C RAB GTPase homolog 8C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831817, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAB8C
    Official Full Name
    RAB GTPase homolog 8C
    Primary source
    TAIR:AT5G03520
    Locus tag
    AT5G03520
    See related
    Araport:AT5G03520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS RAB HOMOLOG E1D; ATRAB-E1D; ATRAB8C; ATRABE1D; F12E4.300; F12E4_300; RAB GTPase homolog 8C; RAB HOMOLOG E1D; RAB-E1D
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    Genomic context

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    See RAB8C in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (883311..885451)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Mediator complex, subunit Med7 Neighboring gene C2H2-type zinc finger family protein Neighboring gene RAB GTPase homolog C2A Neighboring gene exocyst subunit exo70 family protein A1 Neighboring gene expressed in response to phosphate starvation protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Subcellular localization and functional analysis of the Arabidopsis GTPase RabE. Speth EB, et al. Plant Physiol, 2009 Apr. PMID 19233904, Free PMC Article
    2. Arabidopsis Rab-E GTPases exhibit a novel interaction with a plasma-membrane phosphatidylinositol-4-phosphate 5-kinase. Camacho L, et al. J Cell Sci, 2009 Dec 1. PMID 19903693
    3. CHARACTERIZATION OF A RABE (RAS GENE FROM RAT BRAIN E) GTPASE EXPRESSED DURING MORPHOGENESIS IN THE UNICELLULAR GREEN ALGA MICRASTERIAS DENTICULATA (ZYGNEMATOPHYCEAE, STREPTOPHYTA)(1). Vannerum K, et al. J Phycol, 2012 Jun. PMID 27011085
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036750.1
    NM_120432.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    colocalizes_with plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog 8C
    NP_001031827.1
    • RAB GTPase homolog 8C (RAB8C); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog E1E (TAIR:AT3G09900.1); Has 25713 Blast hits to 25688 proteins in 729 species: Archae - 2; Bacteria - 99; Metazoa - 13473; Fungi - 3651; Plants - 2845; Viruses - 20; Other Eukaryotes - 5623 (source: NCBI BLink).
    NP_195972.1
    • RAB GTPase homolog 8C (RAB8C); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog E1E (TAIR:AT3G09900.1); Has 29771 Blast hits to 29709 proteins in 824 species: Archae - 21; Bacteria - 191; Metazoa - 15611; Fungi - 4242; Plants - 3476; Viruses - 20; Other Eukaryotes - 6210 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      883311..885451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120432.5 → NP_195972.1  RAB GTPase homolog 8C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195972.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q2V3A4, Q8LBQ4, Q9LZD4
      UniProtKB/TrEMBL
      A0A178UJN5, A0A5S9Y120
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

    2. NM_001036750.1 → NP_001031827.1  RAB GTPase homolog 8C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031827.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V885
      Conserved Domains (2) summary
      PTZ00099
      Location:40 → 202
      PTZ00099; rab6; Provisional
      cl21455
      Location:40 → 170
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZD4.1

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