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    MTHSC70-2 mitochondrial HSO70 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830818, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MTHSC70-2
    Official Full Name
    mitochondrial HSO70 2
    Primary source
    TAIR:AT5G09590
    Locus tag
    AT5G09590
    See related
    Araport:AT5G09590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F17I14.220; F17I14_220; HEAT SHOCK COGNATE; HEAT SHOCK PROTEIN 70; HSC70-5; mitochondrial HSO70 2
    Summary
    heat shock protein 70 (Hsc70-5); nuclear
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    Genomic context

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    See MTHSC70-2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (2975436..2978750)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene heat shock protein Neighboring gene ncRNA Neighboring gene succinate dehydrogenase 3-1 Neighboring gene pumilio 21 Neighboring gene Octicosapeptide/Phox/Bem1p family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mitochondrial proteins AtHscB and AtIsu1 involved in Fe-S cluster assembly interact with the Hsp70-type chaperon AtHscA2 and modulate its catalytic activity. Leaden L, et al. Mitochondrion, 2014 Nov. PMID 25462017
    2. Virus induction of heat shock protein 70 reflects a general response to protein accumulation in the plant cytosol. Aparicio F, et al. Plant Physiol, 2005 May. PMID 15805473, Free PMC Article
    3. Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses. Noël LD, et al. Plant Cell, 2007 Dec. PMID 18065690, Free PMC Article
    4. Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family. Sung DY, et al. Plant Physiol, 2001 Jun. PMID 11402207, Free PMC Article
    5. Proteomic approach to identify novel mitochondrial proteins in Arabidopsis. Kruft V, et al. Plant Physiol, 2001 Dec. PMID 11743114, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results suggest that AtHscA2 in cooperation with AtIsu1 and AtHscB play an important role in the regulation of the Fe-S cluster assembly pathway in plant mitochondria. [AtHscA2]
      Title: The mitochondrial proteins AtHscB and AtIsu1 involved in Fe-S cluster assembly interact with the Hsp70-type chaperon AtHscA2 and modulate its catalytic activity.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120996.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein folding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to virus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrial matrix TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    mitochondrial HSO70 2
    NP_196521.1
    • mitochondrial HSO70 2 (MTHSC70-2); FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to salt stress, response to virus, response to heat; LOCATED IN: mitochondrion, cell wall, plasma membrane, chloroplast, mitochondrial matrix; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Chaperone DnaK (InterPro:IPR012725), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: mitochondrial heat shock protein 70-1 (TAIR:AT4G37910.1); Has 35090 Blast hits to 34955 proteins in 4871 species: Archae - 160; Bacteria - 17405; Metazoa - 3531; Fungi - 1665; Plants - 1246; Viruses - 305; Other Eukaryotes - 10778 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2975436..2978750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120996.4 → NP_196521.1  mitochondrial HSO70 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196521.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LDZ0
      UniProtKB/TrEMBL
      A0A5S9Y3J7, A0A654FZW3
      Conserved Domains (1) summary
      PRK00290
      Location:59 → 682
      dnaK; molecular chaperone DnaK; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LDZ0.1

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