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    BOB1 HSP20-like chaperones superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835421, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BOB1
    Official Full Name
    HSP20-like chaperones superfamily protein
    Primary source
    TAIR:AT5G53400
    Locus tag
    AT5G53400
    See related
    Araport:AT5G53400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BOBBER1; MYN8.1; MYN8_1
    Summary
    Encodes BOBBER1 (BOB1), a non-canonical small heat shock protein required for both development and thermotolerance. BOB1 is cytoplasmic at basal temperatures but forms heat shock granules containing canonical small heat shock proteins at high temperatures.
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    Genomic context

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    See BOB1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (21661444..21663843)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene O-acyltransferase (WSD1-like) family protein Neighboring gene O-acyltransferase (WSD1-like) family protein Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene CCT motif family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic Interactions Between BOB1 and Multiple 26S Proteasome Subunits Suggest a Role for Proteostasis in Regulating Arabidopsis Development. Silverblatt-Buser EW, et al. G3 (Bethesda), 2018 Mar 28. PMID 29487187, Free PMC Article
    2. Partitioning the apical domain of the Arabidopsis embryo requires the BOBBER1 NudC domain protein. Jurkuta RJ, et al. Plant Cell, 2009 Jul. PMID 19648297, Free PMC Article
    3. BOBBER1 is a noncanonical Arabidopsis small heat shock protein required for both development and thermotolerance. Perez DE, et al. Plant Physiol, 2009 Sep. PMID 19571304, Free PMC Article
    4. Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Elrouby N, et al. Proc Natl Acad Sci U S A, 2010 Oct 5. PMID 20855607, Free PMC Article
    5. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BOB1 mediated protein folding and proteasome mediated protein degradation form a functional proteostasis module required for ensuring normal plant development.
      Title: Genetic Interactions Between BOB1 and Multiple 26S Proteasome Subunits Suggest a Role for Proteostasis in Regulating Arabidopsis Development.
    2. BOB1 encodes a novel sHSP with dual function in development and thermotolerance. [BOBBER1] [BOB1]
      Title: BOBBER1 is a noncanonical Arabidopsis small heat shock protein required for both development and thermotolerance.
    3. Data indicate a possible role for BOBBER1 in synthesis or transport of proteins involved in patterning the Arabidopsis embryo. [BOBBER1]
      Title: Partitioning the apical domain of the Arabidopsis embryo requires the BOBBER1 NudC domain protein.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_124719.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within developmental process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within flower structural organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in flower structural organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within heat acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in heat acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within inflorescence meristem growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein folding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within specification of floral organ number IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stamen morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    HSP20-like chaperones superfamily protein
    NP_200152.1
    • BOBBER1 (BOB1); CONTAINS InterPro DOMAIN/s: CS-like domain (InterPro:IPR007052), HSP20-like chaperone (InterPro:IPR008978), CS domain (InterPro:IPR017447); BEST Arabidopsis thaliana protein match is: HSP20-like chaperones superfamily protein (TAIR:AT4G27890.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21661444..21663843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124719.4 → NP_200152.1  HSP20-like chaperones superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200152.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LAL5, Q9LV09
      UniProtKB/TrEMBL
      A0A178UNA0, A0A5S9YE67
      Conserved Domains (1) summary
      cd06467
      Location:147 → 231
      p23_NUDC_like; p23_like domain of NUD (nuclear distribution) C and similar proteins. Aspergillus nidulas (An) NUDC is needed for nuclear movement. AnNUDC is localized at the hyphal cortex, and binds NUDF at spindle pole bodies (SPBs) and in the cytoplasm at different ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LV09.1

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