diphthamide synthesis DPH2 family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: diphthamide synthesis DPH2 family protein
Primary source: TAIR:AT5G62030
Locus tag: AT5G62030
See related: Araport:AT5G62030
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MTG10.5; MTG10_5
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (24918479..24920955)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CYP20-3 links photosynthetic electron transport and redox regulation to the folding of SAT1, thereby enabling the cysteine-based thiol biosynthesis pathway to adjust to light and stress conditions. [CYP20-3]
Title: A cyclophilin links redox and light signals to cysteine biosynthesis and stress responses in chloroplasts.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_125596.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 2-(3-amino-3-carboxypropyl)histidine synthase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in maintenance of translational fidelity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein histidyl modification to diphthamide	IEA Inferred from Electronic Annotation more info
involved_in regulation of translational fidelity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: diphthamide synthesis DPH2 family protein

NP_201009.1

diphthamide synthesis DPH2 family protein; CONTAINS InterPro DOMAIN/s: Diphthamide synthesis, DHP1 (InterPro:IPR016435), Diphthamide synthesis, DPH1/DHP2 (InterPro:IPR002728); BEST Arabidopsis thaliana protein match is: diphthamide synthesis DPH2 family protein (TAIR:AT3G59630.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

24918479..24920955

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_125596.4 → NP_201009.1 diphthamide synthesis DPH2 family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_201009.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178UKW5, Q8RWW3, Q9FIT5

Conserved Domains (1) summary

pfam01866
Location:70 → 373

Diphthamide_syn; Putative diphthamide synthesis protein