ZAT11 C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ZAT11
Official Full Name: C2H2 and C2HC zinc fingers superfamily protein
Primary source: TAIR:AT2G37430
Locus tag: AT2G37430
See related: Araport:AT2G37430
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F3G5.22; F3G5_22; zinc finger of Arabidopsis thaliana 11
Summary: Encodes a member of the zinc finger family of transcriptional regulators. It is expressed in many root tips, primary roots, cotyledons and hypocotyl. The protein is localized to the nucleus. Overexpression of ZAT11 causes increased root growth and increased sensitivity to nickel ions.
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Genomic context

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See ZAT11 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 1

Sequence:: Chromosome: 2; NC_003071.7 (15706285..15707224)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ZAT11 is a dual function transcriptional regulator that positively regulates primary root growth but negatively regulates nickel tolerance.
Title: ZAT11, a zinc finger transcription factor, is a negative regulator of nickel ion tolerance in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_129298.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to nickel ion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within regulation of root development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: C2H2 and C2HC zinc fingers superfamily protein

NP_181279.1

C2H2 and C2HC zinc fingers superfamily protein; FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, zinc ion binding, nucleic acid binding; INVOLVED IN: response to chitin, regulation of transcription; LOCATED IN: intracellular; EXPRESSED IN: cotyledon, root, petiole; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087); BEST Arabidopsis thaliana protein match is: C2H2-type zinc finger family protein (TAIR:AT3G53600.1); Has 5065 Blast hits to 4182 proteins in 136 species: Archae - 0; Bacteria - 0; Metazoa - 4138; Fungi - 12; Plants - 806; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

15706285..15707224

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_129298.3 → NP_181279.1 C2H2 and C2HC zinc fingers superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_181279.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q39217, Q9SLD4

UniProtKB/TrEMBL

A0A178VNJ8, A0A5S9X5B4, A0A7G2EF48

Conserved Domains (2) summary

sd00017
Location:49 → 69

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13912
Location:47 → 72

zf-C2H2_6; C2H2-type zinc finger