FEI2 Leucine-rich repeat protein kinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: FEI2
Official Full Name: Leucine-rich repeat protein kinase family protein
Primary source: TAIR:AT2G35620
Locus tag: AT2G35620
See related: Araport:AT2G35620
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: FEI 2; T20F21.18; T20F21_18
Summary: Encodes a plasma membrane localized leucine-rich repeat receptor kinase that is involved in cell wall elongation. Loss of function mutations of FEI1 and FEI2 exhibit defects in root and hypocotyl cell elongation. Double mutants are defective in cell wall biosynthesis and have thick hypocotyls, and short, thick roots.
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Genomic context

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See FEI2 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 15

Sequence:: Chromosome: 2; NC_003071.7 (14960851..14965497, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that Arabidopsis proteins GALT2, GALT5, SOS5, FEI1 and FEI2 act in a single genetic signaling pathway.
Title: Glycosylation of a Fasciclin-Like Arabinogalactan-Protein (SOS5) Mediates Root Growth and Seed Mucilage Adherence via a Cell Wall Receptor-Like Kinase (FEI1/FEI2) Pathway in Arabidopsis.
we demonstrated that FEI2 and SOS5 regulate the production of the cellulosic rays deposited across the inner adherent-layer of seed mucilage.
Title: The FEI2-SOS5 pathway and CELLULOSE SYNTHASE 5 are required for cellulose biosynthesis in the Arabidopsis seed coat and affect pectin mucilage structure.
The protein kinases FEI1 and FEI2 help regulate cell expansion and cell wall biosynthesis through interaction with ACC synthase. [FEI2]
Title: Two leucine-rich repeat receptor kinases mediate signaling, linking cell wall biosynthesis and ACC synthase in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001202755.2

Supported by ESTs:

NM_001336565.1

Supported by ESTs:

NM_001336566.1

Supported by ESTs:

NM_129116.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mucilage biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mucilage biosynthetic process involved in seed coat development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mucilage biosynthetic process involved in seed coat development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in plant-type cell wall biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within plant-type cell wall organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within unidimensional cell growth	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Leucine-rich repeat protein kinase family protein

NP_001189684.1

FEI 2 (FEI2); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat protein kinase family protein (TAIR:AT1G31420.2).

NP_181105.2

FEI 2 (FEI2); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat protein kinase family protein (TAIR:AT1G31420.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

14960851..14965497 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_129116.5 → NP_181105.2 Leucine-rich repeat protein kinase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_181105.2

Status: REVIEWED

UniProtKB/Swiss-Prot

C0LGL9, Q0WLU4, Q9ZQN5

UniProtKB/TrEMBL

A0A178VLP0, A0A5S9X477, A0A654EZ72

Conserved Domains (3) summary

PLN03150
Location:59 → 257

PLN03150; hypothetical protein; Provisional

pfam08263
Location:29 → 69

LRRNT_2; Leucine rich repeat N-terminal domain

cl21453
Location:310 → 572

PKc_like; Protein Kinases, catalytic domain
NM_001336565.1 → NP_001324113.1 Leucine-rich repeat protein kinase family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

C0LGL9, Q0WLU4, Q9ZQN5

UniProtKB/TrEMBL

A0A178VLP0, A0A5S9X477, A0A654EZ72

Conserved Domains (3) summary

PLN03150
Location:59 → 257

PLN03150; hypothetical protein; Provisional

pfam08263
Location:29 → 69

LRRNT_2; Leucine rich repeat N-terminal domain

cl21453
Location:310 → 572

PKc_like; Protein Kinases, catalytic domain
NM_001202755.2 → NP_001189684.1 Leucine-rich repeat protein kinase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001189684.1

Status: REVIEWED

UniProtKB/Swiss-Prot

C0LGL9, Q0WLU4, Q9ZQN5

UniProtKB/TrEMBL

A0A178VLP0, A0A5S9X477, A0A654EZ72

Conserved Domains (3) summary

PLN03150
Location:59 → 257

PLN03150; hypothetical protein; Provisional

pfam08263
Location:29 → 69

LRRNT_2; Leucine rich repeat N-terminal domain

cl21453
Location:310 → 572

PKc_like; Protein Kinases, catalytic domain
NM_001336566.1 → NP_001324112.1 Leucine-rich repeat protein kinase family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

C0LGL9, Q0WLU4, Q9ZQN5

UniProtKB/TrEMBL

A0A178VLP0, A0A5S9X477, A0A654EZ72

Conserved Domains (3) summary

PLN03150
Location:59 → 257

PLN03150; hypothetical protein; Provisional

pfam08263
Location:29 → 69

LRRNT_2; Leucine rich repeat N-terminal domain

cl21453
Location:310 → 572

PKc_like; Protein Kinases, catalytic domain