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    SIGF RNApolymerase sigma-subunit F [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818273, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SIGF
    Official Full Name
    RNApolymerase sigma-subunit F
    Primary source
    TAIR:AT2G36990
    Locus tag
    AT2G36990
    See related
    Araport:AT2G36990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSIG6; RNApolymerase sigma-subunit F; SIG6; SIGMA FACTOR 6; SOLDAT8; T1J8.17; T1J8_17
    Summary
    Encodes a general sigma factor in chloroplasts and is probably responsible for the recognition of sigma 70 type standard bacteria-type multi-subunit RNA polymerase (PEP) promoters in young cotyledons. It is a substrate for regulatory phosphorylation by cpCK2, a nuclear-coded plastid-targeted casein kinase 2, that has been implicated as a key component in plant sigma factor phosphorylation and transcriptional regulation.
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    Genomic context

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    See SIGF in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (15537225..15540139, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene DVL family protein Neighboring gene TCP family transcription factor Neighboring gene non-intrinsic ABC protein 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear-encoded sigma factor 6 (SIG6) is involved in the block of greening response in Arabidopsis thaliana. Alameldin HF, et al. Am J Bot, 2020 Feb. PMID 32002990
    2. AtSIG6, a plastid sigma factor from Arabidopsis, reveals functional impact of cpCK2 phosphorylation. Schweer J, et al. Plant J, 2010 Apr. PMID 20088902, Free PMC Article
    3. Characterization of soldat8, a suppressor of singlet oxygen-induced cell death in Arabidopsis seedlings. Coll NS, et al. Plant Cell Physiol, 2009 Apr. PMID 19273469
    4. Dual temporal role of plastid sigma factor 6 in Arabidopsis development. Loschelder H, et al. Plant Physiol, 2006 Oct. PMID 16905663, Free PMC Article
    5. A nuclear-encoded sigma factor, Arabidopsis SIG6, recognizes sigma-70 type chloroplast promoters and regulates early chloroplast development in cotyledons. Ishizaki Y, et al. Plant J, 2005 Apr. PMID 15807777

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Regulation of SIG6 plays a significant role in plant responses to far-red light exposure during the block of greening response
      Title: Nuclear-encoded sigma factor 6 (SIG6) is involved in the block of greening response in Arabidopsis thaliana.
    2. thf1 variegation was suppressed by a mutation in sigma-FACTOR6.
      Title: Leaf Variegation of Thylakoid Formation1 Is Suppressed by Mutations of Specific σ-Factors in Arabidopsis.
    3. The interaction of DG1 and SIG6 regulates RNA polymerase-dependent chloroplast gene transcription.
      Title: Interaction of the pentatricopeptide-repeat protein DELAYED GREENING 1 with sigma factor SIG6 in the regulation of chloroplast gene expression in Arabidopsis cotyledons.
    4. AtSIG6 is a substrate for regulatory phosphorylation by cpCK2.
      Title: AtSIG6, a plastid sigma factor from Arabidopsis, reveals functional impact of cpCK2 phosphorylation.
    5. Inactivation of the SOLDAT8 protein does not impair oxygen singlet-mediated signaling, but instead enhances light sensitivity. [SIGMA6]
      Title: Characterization of soldat8, a suppressor of singlet oxygen-induced cell death in Arabidopsis seedlings.
    6. AtSIG6 may act as a major general sigma factor in chloroplasts during early plant development.
      Title: A nuclear-encoded sigma factor, Arabidopsis SIG6, recognizes sigma-70 type chloroplast promoters and regulates early chloroplast development in cotyledons.
    7. The developmental expression of Sig6 in plastids is reported.
      Title: Dual temporal role of plastid sigma factor 6 in Arabidopsis development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129255.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sigma factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sigma factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sigma factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within DNA-templated transcription initiation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in cellular response to blue light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to light stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seedling development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNApolymerase sigma-subunit F
    NP_565856.1
    • RNApolymerase sigma-subunit F (SIGF); CONTAINS InterPro DOMAIN/s: RNA polymerase sigma factor, region 2 (InterPro:IPR013325), Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), RNA polymerase sigma-70 region 3 (InterPro:IPR007624), RNA polymerase sigma-70 (InterPro:IPR014284), RNA polymerase sigma factor, region 3/4 (InterPro:IPR013324), RNA polymerase sigma factor, SigB/SigC/SigD, plastid (InterPro:IPR016262), RNA polymerase sigma-70 factor (InterPro:IPR000943), RNA polymerase sigma-70 region 2 (InterPro:IPR007627), RNA polymerase sigma-70 region 4 (InterPro:IPR007630); BEST Arabidopsis thaliana protein match is: RNApolymerase sigma subunit 2 (TAIR:AT1G08540.1); Has 23918 Blast hits to 23899 proteins in 2801 species: Archae - 0; Bacteria - 17084; Metazoa - 1; Fungi - 2; Plants - 241; Viruses - 15; Other Eukaryotes - 6575 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15537225..15540139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129255.3 → NP_565856.1  RNApolymerase sigma-subunit F [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565856.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LD95, Q9SJK8, Q9SMV8
      UniProtKB/TrEMBL
      A0A178VYM5, A0A5S9X4N3
      Conserved Domains (1) summary
      TIGR02997
      Location:247 → 531
      Sig70-cyanoRpoD; RNA polymerase sigma factor, cyanobacterial RpoD-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LD95.1

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