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    IRT2 iron regulated transporter 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827712, updated on 18-Sep-2024

    Summary

    Official Symbol
    IRT2
    Official Full Name
    iron regulated transporter 2
    Primary source
    TAIR:AT4G19680
    Locus tag
    AT4G19680
    See related
    Araport:AT4G19680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATIRT2; iron regulated transporter 2; IRON REGULATED TRANSPORTER 2; T16H5.40; T16H5_40
    Summary
    encodes an iron transporter whose expression is induced by iron and zinc deficiency. Gene is specifically expressed in the external cell layers of the root subapical zone.
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    Genomic context

    See IRT2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (10703348..10704838)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene NPR1-like protein 4 Neighboring gene RING/U-box superfamily protein Neighboring gene iron-regulated transporter 1 Neighboring gene ncRNA

    Pathways from PubChem

    General protein information

    Preferred Names
    iron regulated transporter 2
    NP_001031670.1
    • iron regulated transporter 2 (IRT2); FUNCTIONS IN: zinc ion transmembrane transporter activity, iron ion transmembrane transporter activity; INVOLVED IN: zinc ion transport, cellular response to iron ion starvation, iron ion transport; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: root epidermis; CONTAINS InterPro DOMAIN/s: Zinc/iron permease, fungal/plant (InterPro:IPR004698), Zinc/iron permease (InterPro:IPR003689); BEST Arabidopsis thaliana protein match is: iron-regulated transporter 1 (TAIR:AT4G19690.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_193703.2
    • iron regulated transporter 2 (IRT2); FUNCTIONS IN: zinc ion transmembrane transporter activity, iron ion transmembrane transporter activity; INVOLVED IN: zinc ion transport, cellular response to iron ion starvation, iron ion transport; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: root epidermis; CONTAINS InterPro DOMAIN/s: Zinc/iron permease, fungal/plant (InterPro:IPR004698), Zinc/iron permease (InterPro:IPR003689); BEST Arabidopsis thaliana protein match is: iron-regulated transporter 1 (TAIR:AT4G19690.2); Has 1381 Blast hits to 1243 proteins in 190 species: Archae - 0; Bacteria - 10; Metazoa - 183; Fungi - 601; Plants - 483; Viruses - 0; Other Eukaryotes - 104 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10703348..10704838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118088.4NP_193703.2  iron regulated transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193703.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81850
      Conserved Domains (1) summary
      cl00437
      Location:1249
      Zip; ZIP Zinc transporter
    2. NM_001036593.2NP_001031670.1  iron regulated transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031670.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81850, Q2V3G9, Q5M756
      UniProtKB/TrEMBL
      A0A178UYS5, A0A5S9XUV2, A0A654FQZ2, A0A7G2F0X8
      Conserved Domains (1) summary
      PLN02159
      Location:1350
      PLN02159; Fe(2+) transport protein