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    UBP18 ubiquitin-specific protease 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829295, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBP18
    Official Full Name
    ubiquitin-specific protease 18
    Primary source
    TAIR:AT4G31670
    Locus tag
    AT4G31670
    See related
    Araport:AT4G31670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F28M20.140; F28M20_140; ubiquitin-specific protease 18
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    Genomic context

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    See UBP18 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (15335743..15339613, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Transcriptional factor B3 family protein Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene Transcriptional factor B3 family protein Neighboring gene transcriptional factor B3 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SIS8, a putative mitogen-activated protein kinase kinase kinase, regulates sugar-resistant seedling development in Arabidopsis. Huang Y, et al. Plant J, 2014 Feb. PMID 24320620
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_119316.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-specific protease 18
    NP_194895.1
    • ubiquitin-specific protease 18 (UBP18); FUNCTIONS IN: cysteine-type endopeptidase activity, ubiquitin thiolesterase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, MYND-type (InterPro:IPR002893), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 19 (TAIR:AT2G24640.1); Has 9064 Blast hits to 8065 proteins in 324 species: Archae - 2; Bacteria - 451; Metazoa - 4433; Fungi - 1481; Plants - 999; Viruses - 9; Other Eukaryotes - 1689 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15335743..15339613 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119316.5 → NP_194895.1  ubiquitin-specific protease 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194895.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81780, Q67XW5, Q682A0
      UniProtKB/TrEMBL
      A0A178UXK6, A0A5S9XYD7, A0A654FV19
      Conserved Domains (2) summary
      cd02661
      Location:167 → 472
      Peptidase_C19E; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam01753
      Location:61 → 98
      zf-MYND; MYND finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q67XW5.2

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