APTX APRATAXIN-like protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: APTX
Official Full Name: APRATAXIN-like protein
Primary source: TAIR:AT5G01310
Locus tag: AT5G01310
See related: Araport:AT5G01310
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: APRATAXIN-like; T10O8.20; T10O8_20
Summary: Encodes a protein that has adenylylsulfate sulfohydrolase activity (E.C. 3.6.2.1) in vitro. This locus has been split into two based on data presented in PMID:22372440. The first annotated exon of the existing AT5G01310.1 model (TAIR10) with part of the first intron becomes a new locus AT5G01305 (encodes a bHLH proteins ROX1). The 3' part retains the original locus name: AT5G01310 (encodes APTX).
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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NM_120209.2

Function	Evidence Code	Pubs
enables adenylylsulfatase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within purine ribonucleotide metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within sulfur compound metabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

NP_195751.2

APRATAXIN-like (APTX); FUNCTIONS IN: adenylylsulfatase activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: sulfur metabolic process, purine ribonucleotide metabolic process, regulation of transcription; LOCATED IN: intracellular, nucleus, chloroplast; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Appr-1-p processing (InterPro:IPR002589), Histidine triad (HIT) protein (InterPro:IPR001310), Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Histidine triad motif (InterPro:IPR011151), Helix-loop-helix DNA-binding (InterPro:IPR011598), Histidine triad-like motif (InterPro:IPR011146), Histidine triad, conserved site (InterPro:IPR019808); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G21330.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).