U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ASN3 asparagine synthetase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830888, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ASN3
    Official Full Name
    asparagine synthetase 3
    Primary source
    TAIR:AT5G10240
    Locus tag
    AT5G10240
    See related
    Araport:AT5G10240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    asparagine synthetase 3; F18D22.10; F18D22_10
    Summary
    Encodes asparagine synthetase (ASN3).
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ASN3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Sequence:
    Chromosome: 5; NC_003076.8 (3212651..3216551, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene annexin 7 Neighboring gene tRNA-Arg Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene RAB GTPase homolog H1E Neighboring gene cyclin-dependent kinase C;1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Reciprocal regulation of distinct asparagine synthetase genes by light and metabolites in Arabidopsis thaliana. Lam HM, et al. Plant J, 1998 Nov. PMID 9881155
    2. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001036787.1
    NM_121062.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables asparagine synthase (glutamine-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aspartate-ammonia ligase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-asparagine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within asparagine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    asparagine synthetase 3
    NP_001031864.1
    • asparagine synthetase 3 (ASN3); FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity; INVOLVED IN: asparagine biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 2 (TAIR:AT5G65010.1); Has 13137 Blast hits to 12731 proteins in 2385 species: Archae - 388; Bacteria - 8359; Metazoa - 215; Fungi - 297; Plants - 415; Viruses - 9; Other Eukaryotes - 3454 (source: NCBI BLink).
    NP_196586.1
    • asparagine synthetase 3 (ASN3); FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity; INVOLVED IN: asparagine biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 2 (TAIR:AT5G65010.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3212651..3216551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121062.5 → NP_196586.1  asparagine synthetase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196586.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LEA1, Q9LFU1, Q9ZST7
      UniProtKB/TrEMBL
      A0A178UAJ4, A0A5S9Y2Y1
      Conserved Domains (3) summary
      PLN02549
      Location:1 → 577
      PLN02549; asparagine synthase (glutamine-hydrolyzing)
      cd00712
      Location:2 → 192
      AsnB; Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a ...
      pfam00733
      Location:210 → 511
      Asn_synthase; Asparagine synthase

    2. NM_001036787.1 → NP_001031864.1  asparagine synthetase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031864.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UAJ4, A0A5S9Y2Y1, F4KGS3
      Conserved Domains (3) summary
      PLN02549
      Location:1 → 576
      PLN02549; asparagine synthase (glutamine-hydrolyzing)
      cd00712
      Location:2 → 191
      AsnB; Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a ...
      pfam00733
      Location:209 → 510
      Asn_synthase; Asparagine synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFU1.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.