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    DOT3 Phototropic-responsive NPH3 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830889, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DOT3
    Official Full Name
    Phototropic-responsive NPH3 family protein
    Primary source
    TAIR:AT5G10250
    Locus tag
    AT5G10250
    See related
    Araport:AT5G10250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DEFECTIVELY ORGANIZED TRIBUTARIES 3; F18D22.20; F18D22_20
    Summary
    Encodes a protein with an N-terminal BTB/POZ domain and a C-terminal NPH3 family domain. dot3 mutants have defects in shoot and primary root growth and produce an aberrant parallel venation pattern in juvenile leaves.
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    Genomic context

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    See DOT3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (3216881..3219436, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene asparagine synthetase 3 Neighboring gene RAB GTPase homolog H1E Neighboring gene cyclin-dependent kinase C;1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vein patterning screens and the defectively organized tributaries mutants in Arabidopsis thaliana. Petricka JJ, et al. Plant J, 2008 Oct. PMID 18643975
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_121063.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cotyledon vascular tissue pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf vascular tissue pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phloem or xylem histogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within primary root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within shoot system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Phototropic-responsive NPH3 family protein
    NP_196587.1
    • DEFECTIVELY ORGANIZED TRIBUTARIES 3 (DOT3); FUNCTIONS IN: signal transducer activity; INVOLVED IN: in 6 processes; LOCATED IN: cellular_component unknown; EXPRESSED IN: leaf primordium; CONTAINS InterPro DOMAIN/s: NPH3 (InterPro:IPR004249), BTB/POZ fold (InterPro:IPR011333), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: Phototropic-responsive NPH3 family protein (TAIR:AT5G64330.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3216881..3219436 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343097.1 → NP_001330410.1  Phototropic-responsive NPH3 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAS4, A0A5S9Y556, A0A654G002

    2. NM_121063.2 → NP_196587.1  Phototropic-responsive NPH3 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196587.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LFU0
      UniProtKB/TrEMBL
      A0A178UCC7
      Conserved Domains (3) summary
      smart00225
      Location:53 → 153
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam03000
      Location:214 → 463
      NPH3; NPH3 family
      cl02518
      Location:47 → 153
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFU0.1

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