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    CDKC;1 cyclin-dependent kinase C;1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830891, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDKC;1
    Official Full Name
    cyclin-dependent kinase C;1
    Primary source
    TAIR:AT5G10270
    Locus tag
    AT5G10270
    See related
    Araport:AT5G10270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cyclin-dependent kinase C;1; F18D22.40; F18D22_40
    Summary
    Encodes CDKC;1, part of a CDKC kinase complex that is targeted by Cauliflower mosaic virus (CaMV) for transcriptional activation of viral genes. Also regulates plant growth and development.
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    Genomic context

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    See CDKC;1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (3221493..3224788, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene asparagine synthetase 3 Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene RAB GTPase homolog H1E Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cyclin-dependent kinase-activating kinases CDKD;1 and CDKD;3 are essential for preserving mitotic activity in Arabidopsis thaliana. Takatsuka H, et al. Plant J, 2015 Jun. PMID 25942995
    2. Modulation of RNA polymerase II phosphorylation downstream of pathogen perception orchestrates plant immunity. Li F, et al. Cell Host Microbe, 2014 Dec 10. PMID 25464831, Free PMC Article
    3. Roles of Arabidopsis cyclin-dependent kinase C complexes in cauliflower mosaic virus infection, plant growth, and development. Cui X, et al. Plant Cell, 2007 Apr. PMID 17468259, Free PMC Article
    4. Novel complexes of cyclin-dependent kinases and a cyclin-like protein from Arabidopsis thaliana with a function unrelated to cell division. Barrôco RM, et al. Cell Mol Life Sci, 2003 Feb. PMID 12678503, Free PMC Article
    5. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At5g10270(CDKD;1) is essential for preserving mitotic activity in Arabidopsis thaliana.
      Title: Cyclin-dependent kinase-activating kinases CDKD;1 and CDKD;3 are essential for preserving mitotic activity in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121065.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within leaf development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to virus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cyclin-dependent kinase C;1
    NP_196589.1
    • cyclin-dependent kinase C;1 (CDKC;1); FUNCTIONS IN: kinase activity; INVOLVED IN: response to virus, leaf development; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cyclin dependent kinase group C2 (TAIR:AT5G64960.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3221493..3224788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121065.3 → NP_196589.1  cyclin-dependent kinase C;1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196589.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LFT8
      UniProtKB/TrEMBL
      A0A178UJP9, A0A5S9Y2Y4
      Conserved Domains (1) summary
      cd07840
      Location:26 → 325
      STKc_CDK9_like; Catalytic domain of Cyclin-Dependent protein Kinase 9-like Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFT8.1

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