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    SRO5 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836372, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SRO5
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT5G62520
    Locus tag
    AT5G62520
    See related
    Araport:AT5G62520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K19B1.13; K19B1_13; similar to RCD one 5
    Summary
    Encodes a protein with similarity to RCD1 but without the WWE domain. The protein does have a PARP signature upstream of the C-terminal protein interaction domain. The PARP signature may bind NAD+ and attach the ADP-ribose-moiety from NAD+ to the target molecule. Its presence suggests a role for the protein in ADP ribosylation. Up-regulated by NaCl. SRO5 and P5CDH (an overlapping gene in the antisense orientation) generate 24-nt and 21-nt siRNAs, which together are components of a regulatory loop controlling reactive oxygen species (ROS) production and stress response.
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    Genomic context

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    See SRO5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (25097944..25099907)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene end binding protein 1B Neighboring gene F-box family protein Neighboring gene aldehyde dehydrogenase 12A1 Neighboring gene ubiquitin-conjugating enzyme 3 Neighboring gene microtubule-associated futsch-like protein Neighboring gene RING/U-box superfamily protein with ARM repeat domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis. Borsani O, et al. Cell, 2005 Dec 29. PMID 16377568, Free PMC Article
    2. Arabidopsis SIMILAR TO RCD-ONE genes are ubiquitous and respond to multiple abiotic stresses through diverse signaling pathways. Zhao X, et al. J Biosci, 2019 Dec. PMID 31894110
    3. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SRO1 has partially overlapping functions with RCD1 in plant response to HgCl2 and H2O2 stress. Analysis of the transcriptional expression of SROs indicated that both of the RCD1 and SRO1 transcripts were up-regulated by HgCl2 and light, not by other stresses, and that of SRO5 was induced by salt
      Title: Arabidopsis SIMILAR TO RCD-ONE genes are ubiquitous and respond to multiple abiotic stresses through diverse signaling pathways.
    2. It was found that SR05 together with P5CDH generates 2 types of SiRNAs.
      Title: Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125646.3
    NM_203252.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within reactive oxygen species metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_201058.1
    • similar to RCD one 5 (SRO5); FUNCTIONS IN: NAD+ ADP-ribosyltransferase activity; INVOLVED IN: oxygen and reactive oxygen species metabolic process, response to salt stress; LOCATED IN: mitochondrion; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Poly(ADP-ribose) polymerase, catalytic domain (InterPro:IPR012317), RST domain of plant C-terminal (InterPro:IPR022003); BEST Arabidopsis thaliana protein match is: similar to RCD one 4 (TAIR:AT3G47720.1); Has 162 Blast hits to 153 proteins in 15 species: Archae - 0; Bacteria - 0; Metazoa - 2; Fungi - 0; Plants - 159; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).
    NP_974981.1
    • similar to RCD one 5 (SRO5); FUNCTIONS IN: NAD+ ADP-ribosyltransferase activity; INVOLVED IN: oxygen and reactive oxygen species metabolic process, response to salt stress; LOCATED IN: mitochondrion; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Poly(ADP-ribose) polymerase, catalytic domain (InterPro:IPR012317); BEST Arabidopsis thaliana protein match is: similar to RCD one 4 (TAIR:AT3G47720.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25097944..25099907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125646.3 → NP_201058.1  uncharacterized protein AT5G62520 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201058.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K6I7, Q8LCY5, Q9FJJ3
      UniProtKB/TrEMBL
      A0A178U7C5, A0A5S9YH14, A0A654GDL0
      Conserved Domains (1) summary
      pfam12174
      Location:241 → 305
      RST; RCD1-SRO-TAF4 (RST) plant domain

    2. NM_203252.1 → NP_974981.1  uncharacterized protein AT5G62520 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974981.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FJJ3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJJ3.1

    Gene LinkOut

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