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    Clathrin light chain protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824352, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Clathrin light chain protein
    Primary source
    TAIR:AT3G51890
    Locus tag
    AT3G51890
    See related
    Araport:AT3G51890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    clathrin light chain 3; CLC3
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (19249475..19251112, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Mitochondrial substrate carrier family protein Neighboring gene high mobility group B1 Neighboring gene sulfate transporter 3;1 Neighboring gene heat shock transcription factor A7A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Clathrin regulates blue light-triggered lateral auxin distribution and hypocotyl phototropism in Arabidopsis. Zhang Y, et al. Plant Cell Environ, 2017 Jan. PMID 27770560
    2. Clathrin light chains regulate hypocotyl elongation by affecting the polarization of the auxin transporter PIN3 in Arabidopsis. Hu T, et al. J Integr Plant Biol, 2021 Nov. PMID 34478221
    3. Clathrin light chains regulate clathrin-mediated trafficking, auxin signaling, and development in Arabidopsis. Wang C, et al. Plant Cell, 2013 Feb. PMID 23424247, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Clathrin light chains regulate hypocotyl elongation by affecting the polarization of the auxin transporter PIN3 in Arabidopsis.
      Title: Clathrin light chains regulate hypocotyl elongation by affecting the polarization of the auxin transporter PIN3 in Arabidopsis.
    2. Loss of clathrin light chain 2 (CLC2) and CLC3 affects endocytosis and lateral distribution of PIN3 thereby impairing blue light-triggered establishment of asymmetric auxin distribution.
      Title: Clathrin regulates blue light-triggered lateral auxin distribution and hypocotyl phototropism in Arabidopsis.
    3. At3g51890 regulates clathrin-mediated trafficking, auxin signaling, and development in Arabidopsis.
      Title: Clathrin light chains regulate clathrin-mediated trafficking, auxin signaling, and development in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_115048.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of clathrin coat of coated pit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of clathrin coat of trans-Golgi network vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    Clathrin light chain protein
    NP_566956.4
    • Clathrin light chain protein; FUNCTIONS IN: structural molecule activity; INVOLVED IN: intracellular protein transport, vesicle-mediated transport; LOCATED IN: clathrin coat of trans-Golgi network vesicle, clathrin coat of coated pit; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Clathrin light chain (InterPro:IPR000996); BEST Arabidopsis thaliana protein match is: Clathrin light chain protein (TAIR:AT2G40060.1); Has 358 Blast hits to 358 proteins in 117 species: Archae - 0; Bacteria - 0; Metazoa - 147; Fungi - 68; Plants - 116; Viruses - 0; Other Eukaryotes - 27 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19249475..19251112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115048.7 → NP_566956.4  Clathrin light chain protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566956.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J5M9, O65024
      UniProtKB/TrEMBL
      A0A178V6Z7, A0A5S9XK05
      Conserved Domains (1) summary
      pfam01086
      Location:5 → 225
      Clathrin_lg_ch; Clathrin light chain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4J5M9.1

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