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    EMB2754 Vacuolar sorting protein 39 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829815, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB2754
    Official Full Name
    Vacuolar sorting protein 39
    Primary source
    TAIR:AT4G36630
    Locus tag
    AT4G36630
    See related
    Araport:AT4G36630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AP22.59; AP22_59; EMBRYO DEFECTIVE 2754
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    Genomic context

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    See EMB2754 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Sequence:
    Chromosome: 4; NC_003075.7 (17271764..17276626, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene GATA transcription factor 19 Neighboring gene tRNA-Ile Neighboring gene Sec14p-like phosphatidylinositol transfer family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct sets of tethering complexes, SNARE complexes, and Rab GTPases mediate membrane fusion at the vacuole in Arabidopsis. Takemoto K, et al. Proc Natl Acad Sci U S A, 2018 Mar 6. PMID 29463724, Free PMC Article
    2. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001342413.1
    NM_119826.8

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of HOPS complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    Vacuolar sorting protein 39
    NP_195381.6
    • EMBRYO DEFECTIVE 2754 (EMB2754); FUNCTIONS IN: small GTPase regulator activity, binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Citron-like (InterPro:IPR001180), Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 (InterPro:IPR019452), Armadillo-type fold (InterPro:IPR016024), Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 (InterPro:IPR019453); Has 871 Blast hits to 660 proteins in 186 species: Archae - 0; Bacteria - 0; Metazoa - 376; Fungi - 292; Plants - 87; Viruses - 0; Other Eukaryotes - 116 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17271764..17276626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119826.8 → NP_195381.6  Vacuolar sorting protein 39 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195381.6

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1P8B4G5, C0Z240, O23218, Q304A1, Q8L5Y0
      UniProtKB/TrEMBL
      A0A178UXB5, A0A5S9XZW4, A0A7G2F6I1
      Conserved Domains (4) summary
      pfam10366
      Location:502 → 612
      Vps39_1; Vacuolar sorting protein 39 domain 1
      pfam00637
      Location:632 → 759
      Clathrin; Region in Clathrin and VPS
      pfam10367
      Location:875 → 984
      Vps39_2; Vacuolar sorting protein 39 domain 2
      cl02434
      Location:69 → 273
      CNH; CNH domain

    2. NM_001342413.1 → NP_001328378.1  Vacuolar sorting protein 39 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2F6I1
      Conserved Domains (4) summary
      pfam10366
      Location:502 → 612
      Vps39_1; Vacuolar sorting protein 39 domain 1
      pfam00637
      Location:632 → 759
      Clathrin; Region in Clathrin and VPS
      pfam10367
      Location:875 → 901
      Vps39_2; Vacuolar sorting protein 39 domain 2
      cl02434
      Location:69 → 273
      CNH; CNH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L5Y0.1

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