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    ZFN2 zinc finger nuclease 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817855, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ZFN2
    Official Full Name
    zinc finger nuclease 2
    Primary source
    TAIR:AT2G32930
    Locus tag
    AT2G32930
    See related
    Araport:AT2G32930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T21L14.13; T21L14_13; zinc finger nuclease 2
    Summary
    Encodes a zinc finger protein.
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    Genomic context

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    See ZFN2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (13965714..13968957, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene B3 domain protein, putative (DUF313) Neighboring gene DCD (Development and Cell Death) domain protein Neighboring gene PDI-like 2-3 Neighboring gene Argonaute family protein Neighboring gene Transducin/WD40 repeat-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Targeted mutagenesis using zinc-finger nucleases in Arabidopsis. Lloyd A, et al. Proc Natl Acad Sci U S A, 2005 Feb 8. PMID 15677315, Free PMC Article
    2. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    3. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128853.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nuclease activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger nuclease 2
    NP_001318339.1
    • zinc finger nuclease 2 (ZFN2); CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571); BEST Arabidopsis thaliana protein match is: Zinc finger C-x8-C-x5-C-x3-H type family protein (TAIR:AT1G04990.1).
    NP_565758.1
    • zinc finger nuclease 2 (ZFN2); CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571); BEST Arabidopsis thaliana protein match is: Zinc finger C-x8-C-x5-C-x3-H type family protein (TAIR:AT1G04990.1); Has 1502 Blast hits to 1018 proteins in 167 species: Archae - 0; Bacteria - 2; Metazoa - 453; Fungi - 164; Plants - 727; Viruses - 0; Other Eukaryotes - 156 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13965714..13968957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336416.1 → NP_001318339.1  zinc finger nuclease 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VT58, A0A5S9X3N5, F4IUS5
      Conserved Domains (1) summary
      pfam00642
      Location:268 → 292
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    2. NM_001336417.1 → NP_001325104.1  zinc finger nuclease 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VT58, A0A1P8B250

    3. NM_128853.2 → NP_565758.1  zinc finger nuclease 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565758.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48772
      UniProtKB/TrEMBL
      A0A178VT58
      Conserved Domains (1) summary
      pfam00642
      Location:264 → 288
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48772.1

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