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    MEE65 Cyclin/Brf1-like TBP-binding protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814656, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MEE65
    Official Full Name
    Cyclin/Brf1-like TBP-binding protein
    Primary source
    TAIR:AT2G01280
    Locus tag
    AT2G01280
    See related
    Araport:AT2G01280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10A8.16; F10A8_16; maternal effect embryo arrest 65
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    Genomic context

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    See MEE65 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    17
    Sequence:
    Chromosome: 2; NC_003071.7 (145676..149394)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene quiescin-sulfhydryl oxidase 2 Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene ribose-5-phosphate isomerase 2 Neighboring gene mediator of RNA polymerase II transcription subunit Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699
    2. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001335052.1
    NM_001335053.1
    NM_126189.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables TBP-class protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chloride:monoatomic cation symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Cyclin/Brf1-like TBP-binding protein
    NP_178237.3
    • maternal effect embryo arrest 65 (MEE65); FUNCTIONS IN: RNA polymerase II transcription factor activity, cation:chloride symporter activity; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Transcription factor TFIIB related (InterPro:IPR000812), Transcription factor TFIIB, cyclin-related (InterPro:IPR013150), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin (InterPro:IPR006670), Brf1-like TBP-binding (InterPro:IPR011665); BEST Arabidopsis thaliana protein match is: Cyclin/Brf1-like TBP-binding protein (TAIR:AT3G09360.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      145676..149394
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126189.4 → NP_178237.3  Cyclin/Brf1-like TBP-binding protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178237.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EQY6, F4IN86
      Conserved Domains (4) summary
      COG1405
      Location:68 → 243
      SUA7; Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]
      cd00043
      Location:69 → 129
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
      pfam07741
      Location:387 → 470
      BRF1; Brf1-like TBP-binding domain
      cl00050
      Location:178 → 237
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    2. NM_001335053.1 → NP_001325196.1  Cyclin/Brf1-like TBP-binding protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2F1, A0A5S9WW99

    3. NM_001335052.1 → NP_001325195.1  Cyclin/Brf1-like TBP-binding protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2F7
    Nucleotide Protein
    Heading Accession and Version

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