BLH8 BEL1-like homeodomain 8 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: BLH8
Official Full Name: BEL1-like homeodomain 8
Primary source: TAIR:AT2G27990
Locus tag: AT2G27990
See related: Araport:AT2G27990
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: BEL1-like homeodomain 8; PNF; POUND-FOOLISH; T1E2.9; T1E2_9
Summary: Encodes a BEL1-like homeobox gene that functions together with PNY in meristem maintenance by regulating the allocation process during vegetative and reproductive development. Both gene products are required for the competence of the SAM to respond properly to floral inductive signals.
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Genomic context

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See BLH8 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 5

Sequence:: Chromosome: 2; NC_003071.7 (11921350..11924748, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The data reveal a potential mechanism by which repression of lateral organ boundary genes by PNY-PNF is essential for flowering.
Title: Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
Regulation of meristem central zone integrity by PNY and PNF is crucial for vegetative and reproductive development.
Title: Regulation of shoot meristem integrity during Arabidopsis vegetative development.
SPL3, SPL4, and SPL5 function is dependent upon PNY and PNF
Title: Regulation of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE genes/microRNA156 module by the homeodomain proteins PENNYWISE and POUND-FOOLISH in Arabidopsis.
PNY and PNF act to restrict organogenesis to the peripheral zone by maintaining a boundary between the central zone and peripheral zone.
Title: The role of PENNYWISE and POUND-FOOLISH in the maintenance of the shoot apical meristem in Arabidopsis.
PNF functions in the inner whorls to regulate flower patterning events. [PNF]
Title: A novel role of BELL1-like homeobox genes, PENNYWISE and POUND-FOOLISH, in floral patterning.
combined lesions in ATH1, PNY and PNF result in a full phenocopy of shoot apical meristem loss-of-function mutants.
Title: Shoot apical meristem function in Arabidopsis requires the combined activities of three BEL1-like homeodomain proteins.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001336138.1

Supported by ESTs:

NM_128358.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within inflorescence development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within internode patterning	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within maintenance of floral meristem identity	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within maintenance of inflorescence meristem identity	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within pattern specification process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within plant organ formation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within secondary shoot formation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: BEL1-like homeodomain 8

NP_180366.1

BEL1-like homeodomain 8 (BLH8); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), POX (InterPro:IPR006563), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: POX (plant homeobox) family protein (TAIR:AT5G02030.1); Has 5076 Blast hits to 5073 proteins in 336 species: Archae - 0; Bacteria - 0; Metazoa - 2093; Fungi - 319; Plants - 2481; Viruses - 0; Other Eukaryotes - 183 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

11921350..11924748 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_128358.3 → NP_180366.1 BEL1-like homeodomain 8 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_180366.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SJJ3

UniProtKB/TrEMBL

A0A178VN67, A0A5S9X1V0, A0A654EYE0

Conserved Domains (2) summary

smart00574
Location:257 → 385

POX; domain associated with HOX domains

pfam05920
Location:442 → 481

Homeobox_KN; Homeobox KN domain
NM_001336138.1 → NP_001324957.1 BEL1-like homeodomain 8 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B1P7