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    RHA2A RING-H2 finger A2A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838073, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RHA2A
    Official Full Name
    RING-H2 finger A2A
    Primary source
    TAIR:AT1G15100
    Locus tag
    AT1G15100
    See related
    Araport:AT1G15100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    RING-H2 finger A2A; RING-H2 FINGER PROTEIN RHA2A
    Summary
    Encodes a putative RING-H2 finger protein RHA2a.
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    Genomic context

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    See RHA2A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (5193284..5194214, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene tRNA-Asn Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene phosphatidyl serine synthase family protein Neighboring gene Ubiquinol-cytochrome C reductase hinge protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis RING finger E3 ligase RHA2b acts additively with RHA2a in regulating abscisic acid signaling and drought response. Li H, et al. Plant Physiol, 2011 Jun. PMID 21478367, Free PMC Article
    2. The Arabidopsis RING finger E3 ligase RHA2a is a novel positive regulator of abscisic acid signaling during seed germination and early seedling development. Bu Q, et al. Plant Physiol, 2009 May. PMID 19286935, Free PMC Article
    3. Interactions between plant RING-H2 and plant-specific NAC (NAM/ATAF1/2/CUC2) proteins: RING-H2 molecular specificity and cellular localization. Greve K, et al. Biochem J, 2003 Apr 1. PMID 12646039, Free PMC Article
    4. Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis. Stone SL, et al. Plant Physiol, 2005 Jan. PMID 15644464, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RHA2b and RHA2a may have redundant yet distinguishable functions in the regulation of abscissic acid responses.
      Title: The Arabidopsis RING finger E3 ligase RHA2b acts additively with RHA2a in regulating abscisic acid signaling and drought response.
    2. RHA2a positively regulates ABA-mediated control of seed germination and early seedling development.
      Title: The Arabidopsis RING finger E3 ligase RHA2a is a novel positive regulator of abscisic acid signaling during seed germination and early seedling development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101378.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    RING-H2 finger A2A
    NP_172962.1
    • RING-H2 finger A2A (RHA2A); FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: response to salt stress, positive regulation of abscisic acid mediated signaling pathway, regulation of response to osmotic stress; LOCATED IN: endomembrane system; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING-H2 finger protein 2B (TAIR:AT2G01150.1); Has 8620 Blast hits to 8597 proteins in 260 species: Archae - 0; Bacteria - 0; Metazoa - 2194; Fungi - 672; Plants - 4576; Viruses - 12; Other Eukaryotes - 1166 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5193284..5194214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101378.3 → NP_172962.1  RING-H2 finger A2A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172962.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4TU39, Q9ZT50
      UniProtKB/TrEMBL
      A0A178WF43, A0A5S9UGT8, A0A654EA37
      Conserved Domains (2) summary
      cd00162
      Location:86 → 127
      RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
      cl17238
      Location:85 → 128
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZT50.1

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