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    NiaP Major facilitator superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820491, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NiaP
    Official Full Name
    Major facilitator superfamily protein
    Primary source
    TAIR:AT3G13050
    Locus tag
    AT3G13050
    See related
    Araport:AT3G13050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtNiaP; MGH6.18; nicotinate transporter
    Summary
    Encodes a plant nicotinate transporter than can also transport trigonelline (N-methylnicotinate).
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    Genomic context

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    See NiaP in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (4176392..4179081)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene hAT transposon superfamily protein Neighboring gene myb-like HTH transcriptional regulator family protein Neighboring gene ncRNA Neighboring gene evolutionarily conserved C-terminal region 5 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals. Jeanguenin L, et al. Funct Integr Genomics, 2012 Mar. PMID 21953179
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001338023.1
    NM_001338024.1
    NM_001338025.1
    NM_112142.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N-methylnicotinate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nicotinate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within N-methylnicotinate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within nicotinate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Major facilitator superfamily protein
    NP_187911.1
    • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: organic cation/carnitine transporter4 (TAIR:AT3G20660.1); Has 38439 Blast hits to 37687 proteins in 2363 species: Archae - 738; Bacteria - 22281; Metazoa - 5017; Fungi - 6515; Plants - 2234; Viruses - 0; Other Eukaryotes - 1654 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4176392..4179081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112142.4 → NP_187911.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187911.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q940M4, Q9LSH7
      UniProtKB/TrEMBL
      A0A178VJK3, A0A5S9XBK5, A0A7G2EL80
      Conserved Domains (1) summary
      cl28910
      Location:27 → 476
      MFS; Major Facilitator Superfamily

    2. NM_001338023.1 → NP_001326468.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q940M4, Q9LSH7
      UniProtKB/TrEMBL
      A0A178VJK3, A0A5S9XBK5, A0A7G2EL80
      Conserved Domains (1) summary
      cl28910
      Location:27 → 476
      MFS; Major Facilitator Superfamily

    3. NM_001338024.1 → NP_001326466.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q940M4, Q9LSH7
      UniProtKB/TrEMBL
      A0A178VJK3, A0A5S9XBK5, A0A7G2EL80
      Conserved Domains (1) summary
      cl28910
      Location:27 → 476
      MFS; Major Facilitator Superfamily

    4. NM_001338025.1 → NP_001326467.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q940M4, Q9LSH7
      UniProtKB/TrEMBL
      A0A178VJK3, A0A5S9XBK5, A0A7G2EL80
      Conserved Domains (1) summary
      cl28910
      Location:27 → 476
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q940M4.1

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