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    ABCC7 multidrug resistance-associated protein 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820498, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCC7
    Official Full Name
    multidrug resistance-associated protein 7
    Primary source
    TAIR:AT3G13100
    Locus tag
    AT3G13100
    See related
    Araport:AT3G13100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMRP7; ATP-binding cassette C7; multidrug resistance-associated protein 7
    Summary
    member of MRP subfamily
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    Genomic context

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    See ABCC7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (4208729..4214530, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene multidrug resistance-associated protein 8 Neighboring gene miscRNA Neighboring gene serine acetyltransferase 2;2 Neighboring gene Ribosomal protein S10p/S20e family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ectopic expression of Arabidopsis ABC transporter MRP7 modifies cadmium root-to-shoot transport and accumulation. Wojas S, et al. Environ Pollut, 2009 Oct. PMID 19467746
    2. Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Bartsch M, et al. Plant Cell, 2006 Apr. PMID 16531493, Free PMC Article
    3. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655
    4. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of MRP7 modifies cadmium root-to-shoot transport and accumulation.
      Title: Ectopic expression of Arabidopsis ABC transporter MRP7 modifies cadmium root-to-shoot transport and accumulation.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001338032.1
    NM_112149.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ABC-type xenobiotic transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to other organism IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    multidrug resistance-associated protein 7
    NP_187917.3
    • multidrug resistance-associated protein 7 (MRP7); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to other organism; LOCATED IN: plasma membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 8 (TAIR:AT3G13090.1); Has 650648 Blast hits to 350565 proteins in 4050 species: Archae - 11697; Bacteria - 531445; Metazoa - 11792; Fungi - 6984; Plants - 5983; Viruses - 13; Other Eukaryotes - 82734 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4208729..4214530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112149.4 → NP_187917.3  multidrug resistance-associated protein 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187917.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LGU0, Q9LK62
      UniProtKB/TrEMBL
      A0A178VBI7
      Conserved Domains (4) summary
      cd03244
      Location:1239 → 1459
      ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
      cd03250
      Location:624 → 824
      ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
      PLN03232
      Location:34 → 1474
      PLN03232; ABC transporter C family member; Provisional
      cl00549
      Location:925 → 1199
      ABC_membrane; ABC transporter transmembrane region

    2. NM_001338032.1 → NP_001325667.1  multidrug resistance-associated protein 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LLY2, A0A654F6N9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LK62.1

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