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    CPK23 calcium-dependent protein kinase 23 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825809, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPK23
    Official Full Name
    calcium-dependent protein kinase 23
    Primary source
    TAIR:AT4G04740
    Locus tag
    AT4G04740
    See related
    Araport:AT4G04740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCPK23; calcium-dependent protein kinase 23; T4B21.15; T4B21_15
    Summary
    member of Calcium Dependent Protein Kinase
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    Genomic context

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    See CPK23 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (2402897..2408737, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene calcium-dependent protein kinase 21 Neighboring gene Ta11-like non-LTR retrotransposon Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Calcium elevation-dependent and attenuated resting calcium-dependent abscisic acid induction of stomatal closure and abscisic acid-induced enhancement of calcium sensitivities of S-type anion and inward-rectifying K channels in Arabidopsis guard cells. Siegel RS, et al. Plant J, 2009 Jul. PMID 19302418, Free PMC Article
    2. ABI1 of Arabidopsis is a protein serine/threonine phosphatase highly regulated by the proton and magnesium ion concentration. Leube MP, et al. FEBS Lett, 1998 Mar 6. PMID 9537523
    3. Calcium-dependent protein kinases CPK21 and CPK23 phosphorylate and activate the iron-regulated transporter IRT1 to regulate iron deficiency in Arabidopsis. Wang Z, et al. Sci China Life Sci, 2023 Nov. PMID 37286859
    4. Plasma membrane-associated calcium signaling modulates cadmium transport. Zhang Y, et al. New Phytol, 2023 Apr. PMID 36567524
    5. Ca(2+)-dependent phosphorylation of NRAMP1 by CPK21 and CPK23 facilitates manganese uptake and homeostasis in Arabidopsis. Fu D, et al. Proc Natl Acad Sci U S A, 2022 Oct 4. PMID 36161952, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Calcium-dependent protein kinases CPK21 and CPK23 phosphorylate and activate the iron-regulated transporter IRT1 to regulate iron deficiency in Arabidopsis.
      Title: Calcium-dependent protein kinases CPK21 and CPK23 phosphorylate and activate the iron-regulated transporter IRT1 to regulate iron deficiency in Arabidopsis.
    2. Plasma membrane-associated calcium signaling modulates cadmium transport.
      Title: Plasma membrane-associated calcium signaling modulates cadmium transport.
    3. Ca(2+)-dependent phosphorylation of NRAMP1 by CPK21 and CPK23 facilitates manganese uptake and homeostasis in Arabidopsis.
      Title: Ca(2+)-dependent phosphorylation of NRAMP1 by CPK21 and CPK23 facilitates manganese uptake and homeostasis in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203743.2
    NM_001340501.1
    NM_001340502.1
    NM_001340503.1
    NM_001340504.1
    NM_001340505.1
    NM_001340506.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein phosphatase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal movement NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    calcium-dependent protein kinase 23
    NP_001190672.1
    • calcium-dependent protein kinase 23 (CPK23); FUNCTIONS IN: in 6 functions; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 21 (TAIR:AT4G04720.1).
    NP_001319868.1
    • calcium-dependent protein kinase 23 (CPK23); FUNCTIONS IN: in 6 functions; INVOLVED IN: response to cadmium ion, protein amino acid phosphorylation, N-terminal protein myristoylation; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 21 (TAIR:AT4G04720.1); Has 128755 Blast hits to 122983 proteins in 3953 species: Archae - 178; Bacteria - 14151; Metazoa - 46216; Fungi - 17196; Plants - 28127; Viruses - 447; Other Eukaryotes - 22440 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      2402897..2408737 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340501.1 → NP_001319868.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M101, Q9ZSA0
      UniProtKB/TrEMBL
      A0A7G2EXQ4

    2. NM_001340502.1 → NP_001328084.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M101, Q9ZSA0
      UniProtKB/TrEMBL
      A0A7G2EXQ4

    3. NM_001340503.1 → NP_001328085.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M101, Q9ZSA0
      UniProtKB/TrEMBL
      A0A7G2EXQ4

    4. NM_001340504.1 → NP_001328083.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M101, Q9ZSA0
      UniProtKB/TrEMBL
      A0A7G2EXQ4

    5. NM_001203743.2 → NP_001190672.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190672.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EXQ4, F4JGW8
      Conserved Domains (4) summary
      smart00220
      Location:84 → 327
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00051
      Location:374 → 433
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd05117
      Location:82 → 326
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
      pfam13499
      Location:374 → 433
      EF-hand_7; EF-hand domain pair

    6. NM_001340505.1 → NP_001328081.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M101, Q9ZSA0
      UniProtKB/TrEMBL
      A0A7G2EXQ4

    7. NM_001340506.1 → NP_001328082.1  calcium-dependent protein kinase 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M101, Q9ZSA0
      UniProtKB/TrEMBL
      A0A7G2EXQ4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M101.1

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