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    PABN1 polyadenylate-binding protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835186, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PABN1
    Official Full Name
    polyadenylate-binding protein 1
    Primary source
    TAIR:AT5G51120
    Locus tag
    AT5G51120
    See related
    Araport:AT5G51120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPABN1; MWD22.6; MWD22_6; polyadenylate-binding protein 1; POLYADENYLATE-BINDING PROTEIN 1
    Summary
    Encodes a homolog of the protein PABN1, a polyadenylation factor subunit.
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    Genomic context

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    See PABN1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (20779327..20781557)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Fe superoxide dismutase 2 Neighboring gene Transcriptional coactivator/pterin dehydratase Neighboring gene ECA1 gametogenesis family protein (DUF1278) Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene Pseudouridine synthase family protein Neighboring gene Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Arabidopsis Fip1 homolog interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits. Forbes KP, et al. J Biol Chem, 2006 Jan 6. PMID 16282318
    2. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. Hunt AG, et al. BMC Genomics, 2008 May 14. PMID 18479511, Free PMC Article
    3. Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm. Kim MH, et al. Cell Stress Chaperones, 2013 Jul. PMID 23334891, Free PMC Article
    4. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    5. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203582.1
    NM_124491.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables poly(A) binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    polyadenylate-binding protein 1
    NP_001190511.1
    • polyadenylate-binding protein 1 (PABN1); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT5G65260.1).
    NP_001190512.1
    • polyadenylate-binding protein 1 (PABN1); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT5G65260.1).
    NP_568751.1
    • polyadenylate-binding protein 1 (PABN1); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT5G10350.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20779327..20781557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203583.1 → NP_001190512.1  polyadenylate-binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190512.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4KBV2
      Conserved Domains (2) summary
      COG0724
      Location:11 → 142
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12306
      Location:19 → 90
      RRM_II_PABPs; RNA recognition motif in type II polyadenylate-binding proteins

    2. NM_124491.3 → NP_568751.1  polyadenylate-binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568751.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LG48, Q93VI4, Q9LU62
      UniProtKB/TrEMBL
      A0A178U874, A0A5S9YCX8, A0A654G9V2
      Conserved Domains (2) summary
      COG0724
      Location:61 → 227
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12306
      Location:104 → 175
      RRM_II_PABPs; RNA recognition motif in type II polyadenylate-binding proteins

    3. NM_001203582.1 → NP_001190511.1  polyadenylate-binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190511.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YCX8, A0A654G9V2, F4KBV3
      Conserved Domains (2) summary
      COG0724
      Location:101 → 265
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12306
      Location:142 → 213
      RRM_II_PABPs; RNA recognition motif in type II polyadenylate-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93VI4.1

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