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    NDL1 N-MYC downregulated-like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835777, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NDL1
    Official Full Name
    N-MYC downregulated-like 1
    Primary source
    TAIR:AT5G56750
    Locus tag
    AT5G56750
    See related
    Araport:AT5G56750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MIK19.22; MIK19_22; N-MYC downregulated-like 1
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    Genomic context

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    See NDL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (22957629..22960916)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene pseudo Neighboring gene serine acetyltransferase 1;1 Neighboring gene transcription repressor-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative expression profiling of AtRAD5B and AtNDL1: Hints towards a role in G protein mediated signaling. Khatri N, et al. Gene Expr Patterns, 2017 Nov. PMID 28865954
    2. N-MYC down-regulated-like proteins regulate meristem initiation by modulating auxin transport and MAX2 expression. Mudgil Y, et al. PLoS One, 2013. PMID 24223735, Free PMC Article
    3. Arabidopsis NDL-AGB1 modules Play Role in Abiotic Stress and Hormonal Responses Along with Their Specific Functions. Katiyar A, et al. Int J Mol Sci, 2019 Sep 24. PMID 31554237, Free PMC Article
    4. Arabidopsis N-MYC DOWNREGULATED-LIKE1, a positive regulator of auxin transport in a G protein-mediated pathway. Mudgil Y, et al. Plant Cell, 2009 Nov. PMID 19948787, Free PMC Article
    5. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results from translational fusion of AtNDL1 and AtRAD5B in seedlings and reproductive organs revealed that both shared similar expression patterns with the highest expression observed in male reproductive organs. Moreover, they shared similar domains of localization in roots, suggesting their potential functioning together in reproductive and root development processes.
      Title: Comparative expression profiling of AtRAD5B and AtNDL1: Hints towards a role in G protein mediated signaling.
    2. AGB1 and NDL1 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots.
      Title: N-MYC down-regulated-like proteins regulate meristem initiation by modulating auxin transport and MAX2 expression.
    3. NDL proteins act in a signaling pathway that modulates root auxin transport and auxin gradients in part by affecting the levels of at least two auxin transport facilitators.[NDL1]
      Title: Arabidopsis N-MYC DOWNREGULATED-LIKE1, a positive regulator of auxin transport in a G protein-mediated pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001345216.1
    NM_125058.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to jasmonic acid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salicylic acid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    N-MYC downregulated-like 1
    NP_200486.1
    • N-MYC downregulated-like 1 (NDL1); CONTAINS InterPro DOMAIN/s: Pollen specific protein SF21 (InterPro:IPR015511), Ndr (InterPro:IPR004142); BEST Arabidopsis thaliana protein match is: N-MYC downregulated-like 3 (TAIR:AT2G19620.1); Has 776 Blast hits to 775 proteins in 111 species: Archae - 2; Bacteria - 48; Metazoa - 563; Fungi - 0; Plants - 132; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22957629..22960916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125058.3 → NP_200486.1  N-MYC downregulated-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200486.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FJT7
      UniProtKB/TrEMBL
      A0A178UI60, A0A5S9YFC3
      Conserved Domains (1) summary
      pfam03096
      Location:21 → 305
      Ndr; Ndr family

    2. NM_001345216.1 → NP_001330516.1  N-MYC downregulated-like 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BB26
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJT7.1

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