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    Uncharacterized protein family (UPF0041) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832131, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Uncharacterized protein family (UPF0041)
    Primary source
    TAIR:AT5G20090
    Locus tag
    AT5G20090
    See related
    Araport:AT5G20090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtMPC1; F28I16.240; F28I16_240; mitochondrial pyruvate carrier 1; MPC1
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (6786834..6788680, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene nudix hydrolase homolog 19 Neighboring gene FAD/NAD(P)-binding oxidoreductase Neighboring gene plant/protein Neighboring gene Dynein light chain type 1 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism. Le XH, et al. Plant Cell, 2021 Aug 31. PMID 34137858, Free PMC Article
    2. The ongoing story: the mitochondria pyruvate carrier 1 in plant stress response in Arabidopsis. Wang M, et al. Plant Signal Behav, 2014. PMID 25482773, Free PMC Article
    3. AGP30: Cd tolerance related gene associate with mitochondrial pyruvate carrier 1. Jing Y, et al. Plant Signal Behav, 2019. PMID 31198086, Free PMC Article
    4. Mitochondrial pyruvate carrier 1 mediates abscisic acid-regulated stomatal closure and the drought response by affecting cellular pyruvate content in Arabidopsis thaliana. Shen JL, et al. BMC Plant Biol, 2017 Nov 22. PMID 29166881, Free PMC Article
    5. NRGA1, a putative mitochondrial pyruvate carrier, mediates ABA regulation of guard cell ion channels and drought stress responses in Arabidopsis. Li CL, et al. Mol Plant, 2014 Oct. PMID 24842572

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism.
      Title: The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism.
    2. AGP30, which specifically expresses in root and is significantly regulated by MPC under Cadmium stress.[MPC1]
      Title: AGP30: Cd tolerance related gene associate with mitochondrial pyruvate carrier 1.
    3. MPC1 is required for cadmium tolerance in Arabidopsis.
      Title: Mitochondrial Pyruvate Carriers Prevent Cadmium Toxicity by Sustaining the TCA Cycle and Glutathione Synthesis.
    4. findings revealed the essential roles of MPC1 and pyruvate in stomatal movement and plant drought resistance
      Title: Mitochondrial pyruvate carrier 1 mediates abscisic acid-regulated stomatal closure and the drought response by affecting cellular pyruvate content in Arabidopsis thaliana.
    5. MPC1 may associate with NRGA1 for mitochondrial pyruvate transport and is involved in abscissic acid mediated stomatal movements in Arabidopsis.[MPC1]
      Title: The ongoing story: the mitochondria pyruvate carrier 1 in plant stress response in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001085137.1
    NM_001125782.1
    NM_001343637.1
    NM_122016.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial pyruvate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial pyruvate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    Uncharacterized protein family (UPF0041)
    NP_001078606.1
    • Uncharacterised protein family (UPF0041); INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Uncharacterised protein family UPF0041 (InterPro:IPR005336); BEST Arabidopsis thaliana protein match is: Uncharacterised protein family (UPF0041) (TAIR:AT4G14695.1); Has 929 Blast hits to 928 proteins in 209 species: Archae - 0; Bacteria - 0; Metazoa - 402; Fungi - 251; Plants - 173; Viruses - 0; Other Eukaryotes - 103 (source: NCBI BLink).
    NP_001119254.1
    • Uncharacterised protein family (UPF0041); INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Uncharacterised protein family UPF0041 (InterPro:IPR005336); BEST Arabidopsis thaliana protein match is: Uncharacterised protein family (UPF0041) (TAIR:AT4G14695.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_197509.1
    • Uncharacterised protein family (UPF0041); INVOLVED IN: biological_process unknown; LOCATED IN: mitochondrion, plasma membrane, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Uncharacterised protein family UPF0041 (InterPro:IPR005336); BEST Arabidopsis thaliana protein match is: Uncharacterised protein family (UPF0041) (TAIR:AT4G14695.1); Has 929 Blast hits to 928 proteins in 209 species: Archae - 0; Bacteria - 0; Metazoa - 402; Fungi - 251; Plants - 173; Viruses - 0; Other Eukaryotes - 103 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6786834..6788680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122016.3 → NP_197509.1  Uncharacterized protein family (UPF0041) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q949R9
      UniProtKB/TrEMBL
      A0A178UR79, A0A5S9Y829
      Conserved Domains (1) summary
      pfam03650
      Location:6 → 107
      MPC; Uncharacterized protein family (UPF0041)

    2. NM_001343637.1 → NP_001330067.1  Uncharacterized protein family (UPF0041) [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q949R9
      UniProtKB/TrEMBL
      A0A178UR79, A0A5S9Y829
      Conserved Domains (1) summary
      pfam03650
      Location:6 → 107
      MPC; Uncharacterized protein family (UPF0041)

    3. NM_001085137.1 → NP_001078606.1  Uncharacterized protein family (UPF0041) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078606.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q949R9
      UniProtKB/TrEMBL
      A0A178UR79, A0A5S9Y829
      Conserved Domains (1) summary
      pfam03650
      Location:6 → 107
      MPC; Uncharacterized protein family (UPF0041)

    4. NM_001125782.1 → NP_001119254.1  Uncharacterized protein family (UPF0041) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119254.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H6E6
      Conserved Domains (1) summary
      pfam03650
      Location:6 → 96
      MPC; uncharacterized protein family (UPF0041)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q949R9.1

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