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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816188, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT2G16870
    Locus tag
    AT2G16870
    See related
    Araport:AT2G16870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12A24.5; F12A24_5
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (7307970..7311796, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene plasma membrane intrinsic protein 2;8 Neighboring gene GCIP-interacting family protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene UDP-Glycosyltransferase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis scaffold protein RACK1A interacts with diverse environmental stress and photosynthesis related proteins. Kundu N, et al. Plant Signal Behav, 2013 May. PMID 23435172, Free PMC Article
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • At2g16870_Arabidopsis_lyrata_ssp._lyrata_CAN1 (e-PCR)
    • At2g16870_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_179279.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT1G64070.1); Has 20392 Blast hits to 15740 proteins in 660 species: Archae - 17; Bacteria - 1396; Metazoa - 2110; Fungi - 75; Plants - 16264; Viruses - 0; Other Eukaryotes - 530 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7307970..7311796 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335494.1 → NP_001323734.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AXY0

    2. NM_001335495.1 → NP_001323733.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AXY0

    3. NM_127240.2 → NP_179279.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179279.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EYI0, Q9ZVX6
      Conserved Domains (7) summary
      PLN03210
      Location:1 → 981
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00031
      Location:552 → 594
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:602 → 624
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:807 → 836
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam01582
      Location:12 → 175
      TIR; TIR domain
      pfam07725
      Location:601 → 620
      LRR_3; Leucine Rich Repeat
      cl21455
      Location:213 → 325
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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